Overview

Microdialysis is used successfully to address various issues in many different clinical fields, such as monitoring for early detection of secondary brain injuries and flap thrombosis. It is also used in Clinical research applications, such as early indication of transplant rejections and anastomosis leakage.

In clinical pharmacology microdialysis is used as a tool to measure target site concentrations of antibiotics or anticancer drugs in different tissues and organs and to subsequently relate target site PK to PD. Leading university hospitals around the globe use M Dialysis’s clinical solutions for continuous monitoring of specific tissues and organs.

As global drug development costs continue to escalate, partially because of the high attrition rate of development candidates, there is increasing pressure to improve the predictability of clinical outcomes from preclinical studies. By understanding the exposure in the appropriate biophase, as well as the effect of a drug candidate at the site of action, selection and optimal doses of the best compound can be improved.

Microdialysis shall not be used as the sole basis for diagnosis or therapy.

Our focus application areas

Reconstructive Surgery  

A reliable and cost-effective tool that controls the success of the flap transfer. It can identify ischemia or a thrombosis and is preferably used on deep buried flaps.

Neuro Monitoring

A unique and effective tool that offers an early indication of secondary injuries and makes it possible to guide and evaluate therapy after Traumatic Brain Injury and Subarachnoid Hemorrhage.

Clinical Research

A unique method for monitoring local tissue chemistry in different tissues and organs after surgery with the potential to identify secondary complications and guide therapy. It can also be used to investigate drug delivery into local tissues and organs.