Bibliography on clinical Microdialysis in Neuro Monitoring

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M Dialysis Att: Katarina Åsberg
Box 5049, SE-121 05 Stockholm, Sweden
Tel +46-8-470 10 20 Fax +46-8-470 10 55
E-mail katarina.asberg@mdialysis.se

Dextran 500 improves recovery of inflammatory markers: an in vitro microdialysis study.

Giorgi-Coll S, Thelin EP, Lindblad C, Tajsic T, Carpenter K, Hutchinson PJ, Helmy A.
Journal of neurotrauma

A Prospective Observational Feasibility Study of Jugular Bulb Microdialysis in Subarachnoid Hemorrhage.

Forsse A, Nielsen TH, Mølstrøm S, Hjelmborg J, Nielsen KS, Nygaard KH, Yilmaz S, Nordström CH, Poulsen FR. Neurocritical care. 2019 Dec 16. doi: 10.1007/s12028-019-00888-0. [Epub ahead of print]

The Impact of Intra-Arterial Papaverine-Hydrochloride on Cerebral Metabolism and Oxygenation for Treatment of Delayed-Onset Post-Subarachnoid Hemorrhage Vasospasm.

Hosmann A, Wang WT, Dodier P, Bavinzski G, Engel A, Herta J, Plöchl W, Reinprecht A, Gruber A.
Neurosurgery. 2019 Dec 3. pii: nyz500. doi: 10.1093/neuros/nyz500. [Epub ahead of print]

Multimodal Regional Brain Monitoring of Tissue Ischemia in Severe Cerebral Venous Sinus Thrombosis.

Simonin A, Rusca M, Saliou G, Levivier M, Daniel RT, Oddo M.
Neurocritical care. 2019 Oct;31(2):297-303. doi: 10.1007/s12028-019-00695-7

Mild hyperventilation in traumatic brain injury – relation to cerebral energy metabolism, pressure autoregulation and clinical outcome.

Wettervik TS, Howells T, Hillered L, Nilsson P, Engquist H, Lewén A, Enblad P, Rostami E.
World neurosurgery World Neurosurg. 2019 Sep 24. pii: S1878-8750(19)32530-6. doi: 10.1016/j.wneu.2019.09.099. [Epub ahead of print]

Role of Bedside Multimodality Monitoring in the Detection of Cerebral Vasospasm Following Subarachnoid Hemorrhage.

Khatibi K, Szeder V, Blanco MB, Tateshima S, Jahan R, Duckwiler G, Vespa P.
Acta neurochirurgica. Supplement. 2020;127:141-144. doi: 10.1007/978-3-030-04615-6_20

Microdialysis Findings in a Patient with New Onset Refractory Non-convulsive Status Epilepticus.

Hurth H, Schlak D, Ebner FH.
Neurocritical care. 2019 Sep 25. doi: 10.1007/s12028-019-00848-8. [Epub ahead of print] No abstract available.

Delayed Ischemic Neurologic Deficit after Aneurysmal Subarachnoid Hemorrhage.

Yamaki VN, Cavalcanti DD, Figueiredo EG.
Asian journal of neurosurgery. 2019 Jul-Sep;14(3):641-647. doi: 10.4103/ajns.AJNS_15_19. Review.

Protocolized Brain Oxygen Optimization in Subarachnoid Hemorrhage.

Rass V, Solari D, Ianosi B, Gaasch M, Kofler M, Schiefecker AJ, Miroz JP, Morelli P, Thomé C, Beer R, Pfausler B, Oddo M, Helbok R.
Neurocritical care. 2019 Jun 19. doi: 10.1007/s12028-019-00753-0. [Epub ahead of print

Copenhagen Head Injury Ciclosporin (CHIC) study: A phase IIa safety, pharmacokinetics and biomarker study of ciclosporin in severe head injury patients.

Kelsen J, Karlsson M, Hansson MJ, Yang Z, Fischer W, Hugerth M, Nordström CH, Åstrand R, Keep MF, Kilbaugh TJ, Wang KKW, Moeller K, Juhler M, Elmér E.
Journal of neurotrauma. 2019 Jun 18

Serum Ngb (Neuroglobin) Is Associated With Brain Metabolism and Functional Outcome of Aneurysmal Subarachnoid Hemorrhage.

Ding CY, Kang DZ, Wang ZL, Lin YX, Jiang CZ, Yu LH, Wang DL, Lin ZY, Gu JJ.
Stroke. 2019 Jun 11:STROKEAHA119025733. doi: 10.1161/STROKEAHA.119.025733. [Epub ahead of print]

Design paper of the “Blood pressure targets in post-resuscitation care and bedside monitoring of cerebral energy state: a randomized clinical trial”.

Mölström S, Nielsen TH, Nordström CH, Hassager C, Møller JE, Kjærgaard J, Möller S, Schmidt H, Toft P.
Trials. 2019 Jun 10;20(1):344. doi: 10.1186/s13063-019-3397-1

Discovery and validation of temporal patterns involved in human brain ketometabolism in cerebral microdialysis fluids of traumatic brain injury patients.

Eiden M, Christinat N, Chakrabarti A, Sonnay S, Miroz JP, Cuenoud B, Oddo M, Masoodi M.
EBioMedicine. 2019 Jun 12. pii: S2352-3964(19)30362-7. doi: 10.1016/j.ebiom.2019.05.054. [Epub ahead of print]

High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury.

Svedung Wettervik T, Howells T, Ronne-Engström E, Hillered L, Lewén A, Enblad P, Rostami E.
Neurocritical care. 2019 May 23. doi: 10.1007/s12028-019-00743-2.

Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury.

Koskinen LD, Sundström N, Hägglund L, Eklund A, Olivecrona M.
Neurocritical care. 2019 May 23. doi: 10.1007/s12028-019-00741-4

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care.

Dyhrfort P, Shen Q, Clausen F, Thulin M, Enblad P, Kamali-MoghaddamM, Hillered L, Lewén A.
J Neurotrauma. 2019 Apr 24. doi:10.1089/neu.2018.6320. [Epub ahead of print]

The Importance of Probe Location for the Interpretation of Cerebral Microdialysis Data in Subarachnoid Hemorrhage Patients.

Kofler M, Gaasch M, Rass V, Schiefecker AJ, Ianosi B, Lindner A, Beer R, Stover JF, Rhomberg P, Pfausler B, Thomé C, Schmutzhard E, Helbok R.
Neurocritical care. 2019 Apr 29. doi: 10.1007/s12028-019-00713-8.

Optimization of the neurosurgical patient in Intensive Care.

Santafé Colomina M, Arikan Abelló F, Sánchez Corral A, Ferrer Roca R.
Medicina intensiva. 2019 Apr 11. pii: S0210-5691(19)30072-5. doi: 10.1016/j.medin.2019.02.011. [Epub ahead of print] English, Spanish.

Dynamic protein changes in the perihaemorrhagic zone of Surgically Treated Intracerebral Haemorrhage Patients.

Tobieson L, Ghafouri B, Zsigmond P, Rossitti S, Hillman J, Marklund N.
Scientific reports. 2019 Feb 28;9(1):3181. doi: 10.1038/s41598-019-39499-2.

The Impact of Intrahospital Transports on Brain Tissue Metabolism in Patients with Acute Brain Injury.

Küchler J, Tronnier F, Smith E, Gliemroth J, Tronnier VM, Ditz C.
Neurocrit Care. 2019 Feb;30(1):216-223. doi: 10.1007/s12028-018-0604-y

Spinal Cord Blood Flow in Patients with Acute Spinal Cord Injuries.

Gallagher MJ, Hogg FRA, Zoumprouli A, Papadopoulos MC, Saadoun S.
J Neurotrauma. 2019 Mar 19;36(6):919-929. doi: 10.1089/neu.2018.5961. Epub 2018 Nov 16

A reduced concentration of brain interstitial amino acids is associated with depression in subarachnoid hemorrhage patients.

Kofler M, Schiefecker AJ, Gaasch M, Sperner-Unterweger B, Fuchs D, Beer R, Ferger B, Rass V, Hackl W, Rhomberg P, Pfausler B, Thomé C, Schmutzhard E, Helbok R.
Sci Rep. 2019 Feb 26;9(1):2811. doi: 10.1038/s41598-019-39569-5.

Cerebrospinal Fluid Glucose and Lactate Levels After Subarachnoid Hemorrhage: A Multicenter Retrospective Study.

Taccone FS, Badenes R, Arib S, Rubulotta F, Mirek S,Franchi F, Gordon S, Nadji A, Crippa IA, Stazi E, Bouhemad B, Lozano Roig A,Creteur J, Bilotta F.
J Neurosurg Anesthesiol. 2019 Feb 11.

Cerebral metabolism is not affected by moderate hyperventilation in patients with traumatic brain injury.

Brandi G, Stocchetti N, Pagnamenta A, Stretti F, Steiger P, Klinzing S.
Crit Care. 2019 Feb 13;23(1):45. doi: 10.1186/s13054-018-2304-6.

Management of Intracranial Pressure Part II: Nonpharmacologic Interventions.

Sacco TL, Davis JG.
Dimens Crit Care Nurs. 2019 Mar/Apr;38(2):61-69. doi: 10.1097/DCC.0000000000000341

Glucose Dynamics of Cortical Spreading Depolarisation in Acute Brain Injury: A Systematic Review.

Stevens AR, Ng I, Helmy A, Hutchinson PJ, Menon D, Ercole A.
J Neurotrauma. 2019 Jan 31. doi: 10.1089/neu.2018.6175. [Epub ahead of print]

Development of a highly sensitive gas chromatography-mass spectrometry method preceded by solid-phase microextraction for the analysis of propofol in low-volume cerebral microdialysate samples.

Guntner AS, Stöcklegger S, Kneidinger M, Illievich U, Buchberger W.
J Sep Sci. 2019 Mar;42(6):1257-1264. doi: 10.1002/jssc.201801066. Epub 2019 Jan 30.

Current Options and Future Directions in Immune Therapy for Glioblastoma.

Lynes J, Sanchez V, Dominah G, Nwankwo A, Nduom E.
Front Oncol. 2018 Dec 5;8:578. doi: 10.3389/fonc.2018.00578. eCollection 2018. Review

The Role of Glycerol-Containing Drugs in Cerebral Microdialysis: A Retrospective Study on the Effects of Intravenously Administered Glycerol.

Forssten MP, Thelin EP, Nelson DW, Bellander BM.
Neurocrit Care. 2018 Nov 14. doi: 10.1007/s12028-018-0643-4. [Epub ahead of print]

Patterns of cerebral tissue oxygen tension and cytoplasmic redox state in bacterial meningitis.

Larsen L, Nielsen TH, Nordström CH, Andersen AB, Schierbeck J, Schulz MK, Poulsen FR.
Acta Anaesthesiol Scand. 2018 Oct 17. doi: 10.1111/aas.13278.

Modulation of cerebral ketone metabolism following traumatic brain injury in humans.

Bernini A, Masoodi M, Solari D, Miroz JP, Carteron L, Christinat N, Morelli P, Beaumont M, Abed-Maillard S, Hartweg M, Foltzer F, Eckert P, Cuenoud B, Oddo M.
J Cereb Blood Flow Metab. 2018 Oct 24:271678X18808947. doi: 10.1177/0271678X18808947. [Epub ahead of print

Cerebral Microdialysis in Neurocritical Care.

Zhou T, Kalanuria A.
Curr Neurol Neurosci Rep. 2018 Oct 23;18(12):101. doi: 10.1007/s11910-018-0915-6. Review

Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade.

Lynes J, Jackson S, Sanchez V, Dominah G, Wang X, Kuek A, Hayes CP, Benzo S, Scott GC, Chittiboina P, Zaghloul KA, Park DM, Wu J, Hourigan CS, Giles AJ, Wu T, Maric D, Chen J, Quezado M, Heiss JD, Gilbert MR, Nduom EK. Neurosurgery. 2018 Sep 4. doi: 10.1093/neuros/nyy392. [Epub ahead of print]

The Impact of Intrahospital Transports on Brain Tissue Metabolism in Patients with Acute Brain Injury.

Kuchler J, Tronnier F, Smith E, Gliemroth J, Tronnier VM, Ditz C.
Neurocrit Care. 2018 Sep 10. doi: 10.1007/s12028-018-0604-y. [Epub ahead of print

Brain Extracellular Interleukin-6 Levels Decrease Following Antipyretic Therapy with Diclofenac in Patients with Spontaneous Subarachnoid Hemorrhage.

Schiefecker AJ, Rass V, Gaasch M, Kofler M, Thomé C, Humpel C, Ianosi B, Hackl WO, Beer R, Pfausler B, Schmutzhard E, Helbok R.
Therapeutic hypothermia and temperature management Ther Hypothermia Temp Manag. 2018 Aug 3. doi: 10.1089/ther.2018.0001.

[Cerebral monitoring of neurocritical patients].

Forsse A, Clausen AH, Nielsen TH, Nordström CH, Poulsen FR.
Ugeskr Laeger. 2018 Jul 23;180(30). pii: V01180025. Danish

The effect of succinate on brain NADH/NAD+ redox state and high energy phosphate metabolism in acute traumatic brain injury.

Stovell MG, Mada MO, Helmy A, Carpenter TA, Thelin EP, Yan JL, Guilfoyle MR, Jalloh I, Howe DJ, Grice P, Mason A, Giorgi-Coll S, Gallagher CN, Murphy MP, Menon DK, Hutchinson PJ, Carpenter KLH.
Scientific reports Sci Rep. 2018 Jul 24;8(1):11140. doi: 10.1038/s41598-018-29255-3

Cerebral oxygenation in traumatic brain injury; Can a non-invasive frequency domain near-infrared spectroscopy device detect changes in brain tissue oxygen tension as well as the established invasive monitor?

Davies DJ, Clancy M, Dehghani H, Lucas SJE, Forcione M, Yakoub KM, Belli A.
Journal of neurotrauma J Neurotrauma. 2018 Jun 7. doi: 10.1089/neu.2018.5667

Persistent Metabolic Disturbance in the Perihemorrhagic Zone Despite a Normalized Cerebral Blood Flow Following Surgery for Intracerebral Hemorrhage.

Tobieson L, Rossitti S, Zsigmond P, Hillman J, Marklund N.
Neurosurgery. 2018 May 21. doi: 10.1093/neuros/nyy179. [Epub ahead of print]

Perifocal metabolism in a patient with brain abscess: insights from cerebral microdialysis.

Rass V, Kofler M, Schiefecker AJ, Gaasch M, Unterhofer C, Thomé C, Rhomberg P, Pfausler B, Beer R, Schmutzhard E, Helbok R.
Journal of neurology, neurosurgery, and psychiatry. 2018 May 7

Persistent Metabolic Disturbance in the Perihemorrhagic Zone Despite a Normalized Cerebral Blood Flow Following Surgery for Intracerebral Hemorrhage.

Tobieson L, Rossitti S, Zsigmond P, Hillman J, Marklund N.
Neurosurgery. 2018 May 21. doi: 10.1093/neuros/nyy179. [Epub ahead of print

A comparison of oxidative lactate metabolism in traumatically injured brain and control brain.

Jalloh I, Helmy A, Howe D, Shannon RJ, Grice P, Mason A, Gallagher CN, Murphy M, Pickard J, Menon D, Carpenter TA, Hutchinson PJ, Carpenter K.
Journal of neurotrauma. 2018 May 18. doi: 10.1089/neu.2017.5459. [Epub ahead of print]

Markedly Deranged Injury Site Metabolism and Impaired Functional Recovery in Acute Spinal Cord Injury Patients With Fever.

Gallagher MJ, Zoumprouli A, Phang I, Schwab JM, Kopp MA, Liebscher T, Papadopoulos MC, Saadoun S.
Critical care medicine. 2018 Apr 6.

The relationship between intracranial pressure and lactate/pyruvate ratio in patients with subarachnoid haemorrhage.

Cesak T, Adamkov J, Habalova J, Poczos P, Kanta M, Bartos M, Hosszu T.
Bratislavske lekarske listy. 2018;119(3):139-142. doi: 10.4149/BLL_2018_027.

Enteral nutrition increases interstitial brain glucose levels in poor-grade subarachnoid hemorrhage patients.

Kofler M, Schiefecker AJ, Beer R, Gaasch M, Rhomberg P, Stover J, Pfausler B, Thomé C, Schmutzhard E, Helbok R.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism”>J Cereb Blood Flow Metab. 2018 Mar;38(3):518-527. doi: 10.1177/0271678X17700434. Epub 2017 Mar 21

Microdialysis as a useful tool to detect cerebral metabolic crises.

de-Lima-Oliveira M, Paschoal Junior F, Bor-Seng-Shu E.
Acta neurochirurgica (Wien). 2018 Feb 15. doi: 10.1007/s00701-018-3484-1. [Epub ahead of print] No abstract available.

A High Performance Application Specific Integrated Circuit for Electrical and Neurochemical Traumatic Brain Injury Monitoring.

Pagkalos I, Rogers M, Boutelle MG, Drakakis EM.
Chemphyschem : a European journal of chemical physics and physical chemistry. 2018 Jan 31. doi: 10.1002/cphc.201701119.

Cerebral metabolic effects of strict versus conventional glycaemic targets following severe traumatic brain injury.

Plummer MP, Notkina N, Timofeev I, Hutchinson PJ, Finnis ME, Gupta AK.
Critical care (London, England). 2018 Jan 25;22(1):16. doi: 10.1186/s13054-017-1933-5

The effect of an adenosine A2A agonist on intra-tumoral concentrations of temozolomide in patients with recurrent glioblastoma.

Jackson S, Weingart J, Nduom EK, Harfi TT, George RT, McAreavey D, Ye X, Anders NM, Peer C, Figg WD, Gilbert M, Rudek MA, Grossman SA.
Fluids and barriers of the CNS. 2018 Jan 15;15(1):2. doi: 10.1186/s12987-017-0088-8

Understanding and monitoring brain injury: the role of cerebral microdialysis.

Oddo M, Hutchinson PJ.
Intensive care medicine. 2017 Dec 23. doi: 10.1007/s00134-017-5031-6.

Multimodality Monitoring: Toward Improved Outcomes.

Gandee R, Miller C.
Seminars in respiratory and critical care medicine. 2017 Dec;38(6):785-792. doi: 10.1055/s-0037-1608774. Epub 2017 Dec 20

Multimodality neuromonitoring in severe pediatric traumatic brain injury.

Young AMH, Guilfoyle MR, Donnelly J, Smielewski P, Agarwal S, Czosnyka M, Hutchinson PJ.
Pediatric research. 2017 Dec 20. doi: 10.1038/pr.2017.215. [Epub ahead of print] Review.

Concentrations of cefuroxime in brain tissue of neurointensive care patients.

Hosmann A, Ritscher LC, Burgmann H, Oesterreicher Z, Jäger W, Poschner S, Knosp E, Reinprecht A, Gruber A, Zeitlinger M.
Antimicrobial agents and chemotherapy. 2017 Dec 4. pii: AAC.02164-17. doi: 10.1128/AAC.02164-17.

Clinical Use of Cerebral Microdialysis in Patients with Aneurysmal Subarachnoid Hemorrhage-State of the Art.

Helbok R, Kofler M, Schiefecker AJ, Gaasch M, Rass V, Pfausler B, Beer R, Schmutzhard E.
Frontiers in neurology. 2017 Nov 3;8:565. doi: 10.3389/fneur.2017.00565. eCollection 2017. Review

Cerebral Microdialysis Monitoring to Improve Individualized Neurointensive Care Therapy: An Update of Recent Clinical Data.

Carteron L, Bouzat P, Oddo M.
Frontiers in neurology. 2017 Nov 13;8:601. doi: 10.3389/fneur.2017.00601. eCollection 2017.

Current Opportunities for Clinical Monitoring of Axonal Pathology in Traumatic Brain Injury.

Tsitsopoulos PP, Abu Hamdeh S, Marklund N.
Frontiers in neurology. 2017 Nov 20;8:599. doi: 10.3389/fneur.2017.00599. eCollection 2017. Review

Cerebrospinal Fluid and Microdialysis Cytokines in Aneurysmal Subarachnoid Hemorrhage: A Scoping Systematic Review.

Zeiler FA, Thelin EP, Czosnyka M, Hutchinson PJ, Menon DK, Helmy A.
Frontiers in neurology. 2017 Aug 8;8:379. doi: 10.3389/fneur.2017.00379. eCollection 2017. Review.

Biofluid biomarkers of traumatic brain injury.

Agoston DV, Shutes-David A, Peskind ER.
Brain injury. 2017;31(9):1195-1203. doi: 10.1080/02699052.2017.1357836

Cerebral microdialysis in TBI-limitations and possibilities.

Nordström CH.
Acta neurochirurgica(Wien). 2017 Oct 12. doi: 10.1007/s00701-017-3339-1. [Epub ahead of print] No abstract available.

A systematic review of cerebral microdialysis and outcomes in TBI: relationships to patient functional outcome, neurophysiologic measures, and tissue outcome.

Zeiler FA, Thelin EP, Helmy A, Czosnyka M, Hutchinson PJA, Menon DK.
Acta neurochirurgica (Wien). 2017 Oct 7. doi: 10.1007/s00701-017-3338-2. [Epub ahead of print] Review.

Does Normobaric Hyperoxia Cause Oxidative Stress in the Injured Brain? A Microdialysis Study Using 8-Iso-Prostaglandin F2α as a Biomarker.

Vidal-Jorge M, Sánchez-Guerrero A, Mur-Bonet G, Castro L, Rădoi A, Riveiro M, Fernández-Prado N, Baena J, Poca MA, Sahuquillo J.
Journal of neurotrauma. 2017 Oct 1;34(19):2731-2742. doi: 10.1089/neu.2017.4992

Detection of metabolic pattern following decompressive craniectomy in severe traumatic brain injury: A microdialysis study.

Gupta D, Singla R, Mazzeo AT, Schnieder EB, Tandon V, Kale SS, Mahapatra AK.
Brain injury. 2017 Sep 19:1-7. doi: 10.1080/02699052.2017.1370553. [Epub ahead of print]

Current and Emerging Technologies for Probing Molecular Signatures of Traumatic Brain Injury.

Ercole A, Magnoni S, Vegliante G, Pastorelli R, Surmacki J, Bohndiek SE, Zanier ER.
Frontiers in neurology. 2017 Aug 30;8:450. doi: 10.3389/fneur.2017.00450. eCollection 2017. Review

Bedside Monitoring of Cerebral Energy State During Cardiac Surgery-A Novel Approach Utilizing Intravenous Microdialysis.

Mölström S, Nielsen TH, Andersen C, Nordström CH, Toft P.
Journal of cardiothoracic and vascular anesthesia. 2017 Aug;31(4):1166-1173. doi: 10.1053/j.jvca.2016.11.001.

The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage.

Rostami E, Engquist H, Howells T, Ronne-Engström E, Nilsson P, Hillered LT, Lewén A, Enblad P.
Frontiers in neurology. 2017 Aug 2;8:369. doi: 10.3389/fneur.2017.00369. eCollection 2017

Non-Ischemic Cerebral Energy Dysfunction at the Early Brain Injury Phase following Aneurysmal Subarachnoid Hemorrhage.

Carteron L, Patet C, Solari D, Messerer M, Daniel RT, Eckert P, Meuli R, Oddo M.
Frontiers in neurology. 2017 Jul 10;8:325. doi: 10.3389/fneur.2017.00325. eCollection 2017.

Cerebrospinal Fluid and Microdialysis Cytokines in Severe Traumatic Brain Injury: A Scoping Systematic Review.

Zeiler FA, Thelin EP, Czosnyka M, Hutchinson PJ, Menon DK, Helmy A.
Frontiers in neurology. 2017 Jul 10;8:331. doi: 10.3389/fneur.2017.00331. eCollection 2017. Review.

Analysis of extracellular brain chemistry during percutaneous dilational tracheostomy: A retrospective study of 19 patients.

Küchler J, Wojak J, Abusamha A, Ditz C, Tronnier VM, Gliemroth J.
Clinical neurology and neurosurgery. 2017 Aug;159:1-5. doi: 10.1016/j.clineuro.2017.05.010. Epub 2017 May 10

Cerebrospinal fluid and brain extracellular fluid in severe brain trauma.

Helbok R, Beer R.
Handbook of clinical neurology. 2017;146:237-258. doi: 10.1016/B978-0-12-804279-3.00014-9.

Aspects on the Physiological and Biochemical Foundations of Neurocritical Care.

Nordström CH, Koskinen LO, Olivecrona M.
Frontiers in neurology. 2017 Jun 19;8:274. doi: 10.3389/fneur.2017.00274. eCollection 2017. Review.

Monitoring the Brain After Cardiac Arrest: a New Era.

Sinha HParnia S.
Current neurology and neuroscience reports. 2017 Aug;17(8):62. doi: 10.1007/s11910-017-0770-x. Review

Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage.

Rostami E, Engquist H, Howells T, Johnson U, Ronne-Engström E, Nilsson P, Hillered L, Lewén A, Enblad P. Journal of neurosurgery. 2017 Jun 2:1-9. doi: 10.3171/2016.11.JNS161140.

Heparin-gold nanoparticles for enhanced microdialysis sampling.

Giorgi-Coll S, Blunt-Foley H, Hutchinson PJ, Carpenter KLH.
Analytical and bioanalytical chemistry. 2017 Jun 29. doi: 10.1007/s00216-017-0447-y

Endovascular Rescue Therapies for Refractory Vasospasm After Subarachnoid Hemorrhage: A Prospective Evaluation Study Using Multimodal, Continuous Event Neuromonitoring.

Albanna W, Weiss M, Müller M, Brockmann MA, Rieg A, Conzen C, Clusmann H, Höllig A, Schubert GA.
Neurosurgery. 2017 Jun 1;80(6):942-949. doi: 10.1093/neuros/nyw132.

Multimodal neurologic monitoring.

Korbakis G, Vespa PM.
Handbook of clinical neurology. 2017;140:91-105. doi: 10.1016/B978-0-444-63600-3.00006-4. Review.

The influence of hyperthermia on intracranial pressure, cerebral oximetry and cerebral metabolism in traumatic brain injury.

Nyholm L, Howells T, Lewén A, Hillered L, Enblad P.
Upsala journal of medical sciences. 2017 May 2:1-8. doi: 10.1080/03009734.2017.1319440.

Brain Multimodality Monitoring: A New Tool in Neurocritical Care of Comatose Patients.

Tasneem N, Samaniego EA, Pieper C, Leira EC, Adams HP, Hasan D, Ortega-Gutierrez S.
Critical care research and practice. 2017;2017:6097265. doi: 10.1155/2017/6097265. Epub 2017 May 7. Review

Advanced monitoring in traumatic brain injury: microdialysis.

Carpenter KL, Young AM, Hutchinson PJ.
Current opinion in critical care. 2017 Apr;23(2):103-109. doi: 10.1097/MCC.0000000000000400.

Systemic and Cerebral Concentration of Nimodipine During Established and Experimental Vasospasm Treatment.

Albanna W, Weiss M, Conzen C, Clusmann H, Schneider T, Reinsch M, Müller M, Wiesmann M, Höllig A, Schubert GA.
World neurosurgery. 2017 Jun;102:459-465. doi: 10.1016/j.wneu.2017.03.062. Epub 2017 Mar 23.

Continuous monitoring and visualization of optimum spinal cord perfusion pressure in patients with acute cord injury.

Chen S, Smieleweski P, Czosnyka M, Papadopoulos MC, Saadoun S. Journal of neurotrauma. 2017 Mar 29. doi: 10.1089/neu.2017.4982. [Epub ahead of print]

Chemical angioplasty with spasmolytics for vasospasm after subarachnoid hemorrhage.

Hejčl A, Cihlář F, Smolka V, Vachata P, Bartoš R, Procházka J, Cihlář J, Sameš M.
Acta neurochirurgica(Wien). 2017 Apr;159(4):713-720. doi: 10.1007/s00701-017-3104-5. Epub 2017 Feb 21.

Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke.

Pinczolits A, Zdunczyk A, Dengler NF, Hecht N, Kowoll CM, Dohmen C, Graf R, Winkler MK, Major S, Hartings JA, Dreier JP, Vajkoczy P, Woitzik J. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2017 May;37(5):1896-1905. doi: 10.1177/0271678X17699629. Epub 2017 Mar 28

Biochemical changes in the injured brain.

Sahu S, Nag DS, Swain A, Samaddar DP.
World journal of biological chemistry. 2017 Feb 26;8(1):21-31. doi: 10.4331/wjbc.v8.i1.21

Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury.

Reis C, Akyol O, Araujo C, Huang L, Enkhjargal B, Malaguit J, Gospodarev V, Zhang JH.
International journal of molecular sciences. 2017 Jan 11;18(1). pii: E129. doi: 10.3390/ijms18010129. Review

Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study.

Tabatabaei P, Visse E, Bergström P, Brännström T, Siesjö P, Bergenheim AT.
Journal of neuro-oncology”. 2017 Jan;131(1):83-92. doi: 10.1007/s11060-016-2271-1

Microdialysis Monitoring in Clinical Traumatic Brain Injury and Its Role in Neuroprotective Drug Development.

Thelin EP, Carpenter KL, Hutchinson PJ, Helmy A.
The AAPS journal. 2017 Jan 9. doi: 10.1208/s12248-016-0027-7. [Epub ahead of print]

Brain Monitoring in Critically Neurologically Impaired Patients.

Jones S, Schwartzbauer G, Jia X.
International journal of molecular sciences 2016 Dec 27;18(1). pii: E43. doi: 10.3390/ijms18010043. Review.

Neural stem cell-based anti-cancer gene therapy: a first-in-human study in recurrent high grade glioma patients.

Portnow J, Synold TW, Badie B, Tirughana R, Lacey SF, D’Apuzzo M, Metz MZ, Najbauer J, Bedell V, Vo T, Gutova M, Frankel P, Chen MY, Aboody KS.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Dec 15. pii: clincanres.1518.2016. [Epub ahead of print]

Bedside cerebral microdialysis monitoring of delayed cerebral hypoperfusion in comatose patients with poor grade aneurysmal subarachnoid haemorrhage.

Patet C, Quintard H, Zerlauth JB, Maibach T, Carteron L, Suys T, Bouzat P, Bervini D, Levivier M, Daniel RT, Eckert P, Meuli R, Oddo M.
Journal of neurology, neurosurgery, and psychiatry. 2016 Dec 7. pii: jnnp-2016-313766. doi: 10.1136/jnnp-2016-313766. [Epub ahead of print]

Regional cerebral blood flow and cellular environment in subarachnoid hemorrhage: A thermal doppler flowmetry and microdialysis study.

Papadopoulos D, Filippidis A, Krommidas G, Vretzakis G, Paterakis K, Komnos A, Fountas KN.
Neurologia i neurochirurgia polska. 2016 Nov 18. pii: S0028-3843(16)30210-9. doi: 10.1016/j.pjnns.2016.11.002. [Epub ahead of print]

Placing intracerebral probes to optimise detection of delayed cerebral ischemia and allow for the prediction of patient outcome in aneurysmal subarachnoid haemorrhage.

Tholance Y, Barcelos GK, Perret-Liaudet A, Omar E, Carrillon R, Grousson S, Lieutaud T, Dailler F, Marinesco S.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Oct 21. pii: 0271678X16675880.

Simultaneous monitoring of potassium, glucose and lactate during spreading depolarisation in the injured human brain – Proof of principle of a novel real-time neurochemical analysis system, continuous online microdialysis.

Rogers ML, Leong CL, Gowers SA, Samper IC, Jewell SL, Khan A, McCarthy L, Pahl C, Tolias CM, Walsh DC, Strong AJ, Boutelle MG.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Oct 18. pii: 0271678X16674486. [Epub ahead of print]

The Role of Multimodal Invasive Monitoring in Acute Traumatic Brain Injury.

Lazaridis C, Robertson CS.
Neurosurgery clinics of North America. 2016 Oct;27(4):509-17. doi: 10.1016/j.nec.2016.05.010. Review

Focally perfused succinate potentiates brain metabolism in head injury patients.

Jalloh I, Helmy A, Howe DJ, Shannon RJ, Grice P, Mason A, Gallagher CN, Stovell MG, van der Heide S, Murphy MP, Pickard JD, Menon DK, Carpenter TA, Hutchinson PJ, Carpenter KL.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Oct 17. pii: 0271678X16672665.

Microdialysate concentration changes do not provide sufficient information to evaluate metabolic effects of lactate supplementation in brain-injured patients.

Dienel GA, Rothman DL, Nordström CH.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Nov;36(11):1844-1864.

Spinal cord injury: is monitoring from the injury site the future?

Saadoun S, Papadopoulos MC.
Critical care (London, England). 2016 Oct 5;20(1):308

Focally perfused succinate potentiates brain metabolism in head injury patients.

Jalloh I, Helmy A, Howe DJ, Shannon RJ, Grice P, Mason A, Gallagher CN, Stovell MG, van der Heide S, Murphy MP, Pickard JD, Menon DK, Carpenter TA, Hutchinson PJ, Carpenter KL.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Oct 17. pii: 0271678X16672665. [Epub ahead of print]

Neuroglucopenia and Metabolic Distress in Two Patients with Viral Meningoencephalitis: A Microdialysis Study.

Kofler M, Schiefecker A, Beer R, Sohm F, Broessner G, Rhomberg P, Lackner P, Pfausler B, Thomé C, Schmutzhard E, Helbok R.
Neurocritical care. 2016 Oct;25(2):273-81. doi: 10.1007/s12028-016-0272-8.

Metabolic profile of injured human spinal cord determined using surface microdialysis.

Chen S, Phang I, Zoumprouli A, Papadopoulos MC, Saadoun S.
Journal of neurochemistry. 2016 Sep 24. doi: 10.1111/jnc.13854

Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study.

Tabatabaei P, Visse E, Bergström P, Brännström T, Siesjö P, Bergenheim AT.
Journal of neuro-oncology. 2016 Sep 23

Cerebral Metabolism and the Role of Glucose Control in Acute Traumatic Brain Injury.

Buitrago Blanco MM, Prashant GN, Vespa PM.
Neurosurgery clinics of North America. 2016 Oct;27(4):453-63. doi: 10.1016/j.nec.2016.05.003. Review

Multimodal brain monitoring in fulminant hepatic failure.

Paschoal FM Jr, Nogueira RC, Ronconi Kde A, de Lima Oliveira M, Teixeira MJ, Bor-Seng-Shu E.
World journal of hepatology. 2016 Aug 8;8(22):915-23. doi: 10.4254/wjh.v8.i22.915. Review

Microdialysis to optimize cord perfusion and drug delivery in spinal cord injury.

Phang I, Zoumprouli A, Papadopoulos MC, Saadoun S.
Annals of neurology

Brain Multimodality Monitoring: Updated Perspectives.

Roh D, Park S., Current neurology and neuroscience reports. 2016 Jun;16(6):56. doi: 10.1007/s11910-016-0659-0. Review

Characterization of the ionic profile of the extracellular space of the injured and ischemic brain: A microdialysis study.

Martínez-Valverde T, Sánchez-Guerrero A, Vidal-Jorge M, Torné R, Castro L, Gándara D, Munar F, Poca MA Dr, Sahuquillo J, Journal of neurotrauma. 2016 May 24

Biochemical indications of cerebral ischaemia and mitochondrial dysfunction in severe brain trauma analysed with regard to type of lesion.

Nordström CH, Nielsen TH, Schalén W, Reinstrup P, Ungerstedt U., A Acta neurochirurgica(Wien). 2016 May 17

Multimodal neuromonitoring for traumatic brain injury: A shift towards individualized therapy.

Makarenko S, Griesdale DE, Gooderham P, Sekhon MS.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2016 Apr;26:8-13. doi: 10.1016/j.jocn.2015.05.065. Review.

Characterization of the serum metabolome following radiation treatment in patients with high-grade gliomas.

Mörén L, Wibom C, Bergström P, Johansson M, Antti H, Bergenheim AT.
Radiation oncology (London, England). 2016 Apr 2;11:51. doi: 10.1186/s13014-016-0626-6

Cerebral Lactate Metabolism After Traumatic Brain Injury.

Patet C, Suys T, Carteron L, Oddo M.
Current neurology and neuroscience reports>. 2016 Apr;16(4):31. doi: 10.1007/s11910-016-0638-

Metabolic crisis occurs with seizures and periodic discharges after brain trauma.

Vespa P, Tubi M, Claassen J, Buitrago-Blanco M, McArthur D, Velazquez AG, Tu B, Prins M, Nuwer M.
Annals of neurology. 2016 Apr;79(4):579-90. doi: 10.1002/ana.24606. Epub 2016 Feb 28

Neuron-Specific Enolase Is Correlated to Compromised Cerebral Metabolism in Patients Suffering from Acute Bacterial Meningitis; An Observational Cohort Study.

Bartek J Jr, Thelin EP, Ghatan PH, Glimaker M, Bellander BM.
PloS one. 2016 Mar 28;11(3):e0152268. doi: 10.1371/journal.pone.0152268. eCollection 2016

Cerebral Microdialysis.

Young B, Kalanuria A, Kumar M, Burke K, Balu R, Amendolia O, McNulty K, Marion B, Beckmann B, Ciocco L, Miller K, Schuele D, Maloney-Wilensky E, Frangos S, Wright D.
Critical care nursing clinics of North America. 2016 Mar;28(1):109-24. doi: 10.1016/j.cnc.2015.09.005. Review.

Intracerebral hypoglycemia and its clinical relevance as a prognostic indicator in severe traumatic brain injury: A cerebral microdialysis study from India.

Gupta DK, Singla R, Kale SS, Sharma BS.
Neurology India. 2016 Mar-Apr;64(2):259-64. doi: 10.4103/0028-3886.177617.

Cerebral microdialysis for assessing intracerebral hypoglycemia: Can it act as a prognostic marker in severe traumatic brain injury?

Sinha VD, Chakrabarty A.,Neurology India. 2016 Mar-Apr;64(2):217-8. doi: 10.4103/0028-3886.177596

The Effect of Packed Red Blood Cell Transfusion on Cerebral Oxygenation and Metabolism After Subarachnoid Hemorrhage.

Kurtz P, Helbok R, Claassen J, Schmidt JM, Fernandez L, Stuart RM, Connolly ES, Lee K, Mayer SA, Badjatia N.
Neurocritical care. 2016 Feb;24(1):118-21. doi: 10.1007/s12028-015-0180-3.

Excitotoxicity and Metabolic Crisis Are Associated with Spreading Depolarizations in Severe Traumatic Brain Injury Patients.

Hinzman JM, Wilson JA, Mazzeo AT, Bullock MR, Hartings J Journal of neurotrauma”. 2016 Mar 18.

Placing intracerebral probes to optimise detection of delayed cerebral ischemia and allow for the prediction of patient outcome in aneurysmal subarachnoid haemorrhage.

Tholance Y, Barcelos GK, Perret-Liaudet A, Omar E, Carrillon R, Grousson S, Lieutaud T, Dailler F, Marinesco S.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Jan 1:271678X16675880. doi: 10.1177/0271678X16675880. [Epub ahead of print

Regional cerebral blood flow and cellular environment in subarachnoid hemorrhage: A thermal doppler flowmetry and microdialysis study.

Papadopoulos D, Filippidis A, Krommidas G, Vretzakis G, Paterakis K, Komnos A, Fountas KN.
Neurologia i neurochirurgia polska. 2017 Jan – Feb;51(1):66-71. doi: 10.1016/j.pjnns.2016.11.002. Epub 2016 Nov 18

Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release after Spontaneous Subarachnoid Hemorrhage.

Schiefecker AJ, Dietmann A, Beer R, Pfausler B, Lackner P, Kofler M, Fischer M, Broessner G, Sohm F, Mulino M, Thomé C, Humpel C, Schmutzhard E, Helbok R.
Current drug targets. 2016 Jan 31.

Clinical Neurochemistry of Subarachnoid Hemorrhage: Toward Predicting Individual Outcomes via Biomarkers of Brain Energy Metabolism.

Tholance Y, Barcelos G, Dailler F, Perret-Liaudet A, Renaud B.
ACS chemical neuroscience. 2015 Dec 16;6(12):1902-5. doi: 10.1021/acschemneuro.5b00299. Epub 2015 Nov 23.

Consensus statement from the 2014 International Microdialysis Forum.

Hutchinson PJ, Jalloh I, Helmy A, Carpenter KL, Rostami E, Bellander BM, Boutelle MG, Chen JW, Claassen J, Dahyot-Fizelier C, Enblad P, Gallagher CN, Helbok R, Hillered L, Le Roux PD, Magnoni S, Mangat HS, Menon DK, Nordström CH, O’Phelan KH, Oddo M, Perez Barcena J, Robertson C, Ronne-Engström E, Sahuquillo J, Smith M, Stocchetti N, Belli A, Carpenter TA, Coles JP, Czosnyka M, Dizdar N, Goodman JC, Gupta AK, Nielsen TH, Marklund N, Montcriol A, O’Connell MT, Poca MA, Sarrafzadeh A, Shannon RJ, Skjøth-Rasmussen J, Smielewski P, Stover JF, Timofeev I, Vespa P, Zavala E, Ungerstedt U.

Intensive care medicine. 2015 Sep;41(9):1517-28. doi: 10.1007/s00134-015-3930-y

Improvement of neuroenergetics by hypertonic lactate therapy in patients with traumatic brain injury is dependent on baseline cerebral lactate/pyruvate ratio.

Quintard H, Patet C, Zerlauth JB, Suys T, Bouzat P, Pellerin L, Meuli R, Magistretti P, Oddo M.
Journal of neurotrauma. 2015 Sep 30. [Epub ahead of print

Extracellular N-Acetylaspartate in Human Traumatic Brain Injury.

Shannon RJ, van der Heide S, Carter EL, Jalloh I, Menon DK, Hutchinson PJ, Carpenter KL.
Journal of neurotrauma. 2015 Aug 14. [Epub ahead of print]

Management of severe spinal cord injury following hyperbaric exposure.

Mathew B, Laden G.
Diving and hyperbaric medicine. 2015 Sep;45(3):210

Detection and quantification of microRNA in cerebral microdialysate.

Bache S, Rasmussen R, Rossing M, Hammer NR, Juhler M, Friis-Hansen L, Nielsen FC, Møller K.
Journal of translational medicine. 2015 May 7;13(1):149.

Cerebral Taurine Levels are Associated with Brain Edema and Delayed Cerebral Infarction in Patients with Aneurysmal Subarachnoid Hemorrhage.

Kofler M, Schiefecker A, Ferger B, Beer R, Sohm F, Broessner G, Hackl W, Rhomberg P, Lackner P, Pfausler B, Thomé C, Schmutzhard E, Helbok R.
Neurocritical care. 2015 Apr 18. [Epub ahead of print]

Regional Brain Monitoring in the Neurocritical Care Unit.

Frontera J, Ziai W, O’Phelan K, Leroux PD, Kirkpatrick PJ, Diringer MN, Suarez JI; Second Neurocritical Care Research Conference Investigators.
Neurocritical care. 2015 Apr 2.

Glycolysis and the significance of lactate in traumatic brain injury.

Carpenter KL, Jalloh I, Hutchinson PJ.
Frontiers in neuroscience. 2015 Apr 8;9:112. doi: 10.3389/fnins.2015.00112. eCollection 2015. Review

Early brain injury after aneurysmal subarachnoid hemorrhage: a multimodal neuromonitoring study.

Helbok R, Schiefecker AJ, Beer R, Dietmann A, Antunes AP, Sohm F, Fischer M, Hackl WO, Rhomberg P, Lackner P, Pfausler B, Thomé C, Humpel C, Schmutzhard E.
Critical care (London, England). 2015 Mar 9

Matrix Metalloproteinase Expression in Contusional Traumatic Brain Injury: A Paired Microdialysis Study.

Guilfoyle MR, Carpenter K, Helmy A, Pickard J, Menon D, Hutchinson PJ.
Journal of neurotrauma. 2015 Apr 9.

Biochemical response to hyperbaric oxygen treatment of a transhemispheric penetrating cerebral gunshot injury.

Thelin EP, Bellander BM, Nekludov M.
Frontiers in neurology. 2015 Mar 23;6:62. doi: 10.3389/fneur.2015.00062. eCollection 2015

Accuracy of brain multimodal monitoring to detect cerebral hypoperfusion after traumatic brain injury*.

Bouzat P, Marques-Vidal P, Zerlauth JB, Sala N, Suys T, Schoettker P, Bloch J, Daniel RT, Levivier M, Meuli R, Oddo M.
Critical care medicine. 2015 Feb;43(2):445-52. doi: 10.1097/CCM.0000000000000720.

Biochemical neuromonitoring of poor-grade aneurysmal subarachnoid hemorrhage: comparative analysis of metabolic events detected by cerebral microdialysis and by retrograde jugular vein catheterization.

Tholance Y, Barcelos GK, Dailler F, Renaud B, Marinesco S, Perret-Liaudet A.
Neurological research. 2015 Feb 10:1743132815Y0000000012. [Epub ahead of print]

Multimodal neuromonitoring for the critical care management of acute coma.

Ltaief Z, Ben-Hamouda N, Suys T, Daniel RT, Rossetti AO, Oddo M.
Revue medicale suisse>. 2014 Dec 10;10(454):2350-5. French

Tissue ischemia microdialysis assessments following severe traumatic haemorrhagic shock: lactate/pyruvate ratio as a new resuscitation end point?

Burša F, Pleva L, Máca J, Sklienka P, Ševčík P.
BMC anesthesiology. 2014 Dec 15;14:118. doi: 10.1186/1471-2253-14-118. eCollection 2014

Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting – a technical approach.

Hillered L, Dahlin AP, Clausen F, Chu J, Bergquist J, Hjort K, Enblad P, Lewén A.
Frontiers in neurology. 2014 Dec 3;5:245. doi: 10.3389/fneur.2014.00245. eCollection 2014. Review

Perioperative microdialysis in meningioma surgery: correlation of cerebral metabolites with clinical outcome.

Balaka C, Stranjalis G, Kalamatianos T, Koutsarnakis C, Bouras T, Boviatsis E, Sakas DE.
Acta neurochirurgica(Wien). 2014 Oct 12. [Epub ahead of print]

Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage.

Jacobsen A, Nielsen TH, Nilsson O, Schalén W, Nordström CH.
Acta neurologica Scandinavica. 2014 Sep;130(3):156-63. doi: 10.1111/ane.12258. Epub 2014 May 3.

Microdialysis Monitoring of CSF Parameters in Severe Traumatic Brain Injury Patients: A Novel Approach.

Thelin EP, Nelson DW, Ghatan PH, Bellander BM.
Frontiers in neurology. 2014 Sep 2;5:159. doi: 10.3389/fneur.2014.00159. eCollection 2014.

International Multidisciplinary Consensus Conference on Multimodality Monitoring: Cerebral Metabolism.

Hutchinson P, O’Phelan K; The Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring.
Neurocrit Care. 2014 Sep 11. [Epub ahead of print]

Lactate shuttling and lactate use as fuel after traumatic brain injury: metabolic considerations.

Dienel GA.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2014 Sep 10. doi: 10.1038/jcbfm.2014.153. [Epub ahead of print]

Bedside Evaluation of Cerebral Energy Metabolism in Severe Community-Acquired Bacterial Meningitis.

Poulsen FR, Schulz M, Jacobsen A, Andersen AB, Larsen L, Schalén W, Nielsen TH, Nordström CH.
Neurocritical care. 2014 Aug 21

Cerebral Glucose Metabolism and Sedation in Brain-injured Patients: A Microdialysis Study.

Hertle DN, Santos E, Hagenston AM, Jungk C, Haux D, Unterberg AW, Sakowitz OW.
Journal of neurosurgical anesthesiology. 2014 Aug 20

Lactate and the lactate-to-pyruvate molar ratio cannot be used as independent biomarkers for monitoring brain energetic metabolism: a microdialysis study in patients with traumatic brain injuries.

Sahuquillo J, Merino MA, Sánchez-Guerrero A, Arikan F, Vidal-Jorge M, Martínez-Valverde T, Rey A, Riveiro M, Poca MA.
PloS one. 2014 Jul 15;9(7):e102540. doi: 10.1371/journal.pone.0102540. eCollection 2014.

Glucose and the injured brain-monitored in the neurointensive care unit.

Rostami E.
Frontiers in neurology. 2014 Jun 6;5:91. doi: 10.3389/fneur.2014.00091. eCollection 2014. Review

Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage – A Xenon-CT and Microdialysis Study.

Rostami E, Engquist H, Johnson U, Howells T, Ronne-Engström E, Nilsson P, Hillered L, Lewén A, Enblad P. Frontiers in neurology. 2014 Jun 2;5:89. doi: 10.3389/fneur.2014.00089. eCollection 2014

Lactate and the injured brain: friend or foe?

Bouzat P, Oddo M.
Current opinion in critical care. 2014 Apr;20(2):133-40. doi: 10.1097/MCC.0000000000000072.PMID:24561705 [PubMed – in process]

Excitotoxicity and metabolic changes in association with infarct progression.

Woitzik J, Pinczolits A, Hecht N, Sandow N, Scheel M, Drenckhahn C, Dreier JP, Vajkoczy P.
Stroke; a journal of cerebral circulation. 2014 Apr;45(4):1183-5. doi: 10.1161/STROKEAHA.113.004475. Epub 2014 Mar 18.

Cerebral Lactate Correlates with Early Onset Pneumonia after Aneurysmal SAH.

Radolf S, Smoll N, Drenckhahn C, Dreier JP, Vajkoczy P, Sarrafzadeh AS.
Translational stroke research. 2014 Apr;5(2):278-85. doi: 10.1007/s12975-013-0292-z. Epub 2013 Oct 17.

Changes in GABA and glutamate concentrations during memory tasks in patients with Parkinson’s disease undergoing DBS surgery.

Buchanan RJ, Darrow DP, Meier KT, Robinson J, Schiehser DM, Glahn DC, Nadasdy Z.
Frontiers in human neuroscience. 2014 Mar 7;8:81. doi: 10.3389/fnhum.2014.00081. eCollection 2014.

Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain.

Bouzat P, Sala N, Suys T, Zerlauth JB, Marques-Vidal P, Feihl F, Bloch J, Messerer M, Levivier M, Meuli R, Magistretti PJ, Oddo M.
Intensive care medicine. 2014 Mar;40(3):412-21. doi: 10.1007/s00134-013-3203-6.

A pilot microdialysis study in brain tumor patients to assess changes in intracerebral cytokine levels after craniotomy and in response to treatment with a targeted anti-cancer agent.

Portnow J, Badie B, Liu X, Frankel P, Mi S, Chen M, Synold TW.
Journal of neuro-oncology. 2014 Mar 15. [Epub ahead of print]

Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial.

Helmy A, Guilfoyle MR, Carpenter KL, Pickard JD, Menon DK, Hutchinson PJ.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism”. 2014 Feb 26. doi: 10.1038/jcbfm.2014.23. [Epub ahead of print]

Cortical spreading depolarization phenomena in patients with traumatic and ischemic brain injuries. Results of a pilot study.

Sueiras M, Sahuquillo J, García-López B, Sánchez-Guerrero A, Poca MA, Santamarina E, Riveiro M, Fabricius M, Strong AJ.
Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias. 2013 Dec 13

Monitoring of cerebral hemodynamics and oxygenation to detect delayed ischemic neurological deficit after aneurysmal subarachnoid hemorrhage.

Seule M, Muroi C, Sikorski C, Keller E.
Acta neurochirurgica. Supplement. 2013;115:57-61. doi: 10.1007/978-3-7091-1192-5_13. Review.

Metabolic Crisis in Severely Head-Injured Patients: Is Ischemia Just the Tip of the Iceberg?

Carre E, Ogier M, Boret H, Montcriol A, Bourdon L, Jean-Jacques R.
Frontiers in neurology. 2013 Oct 11;4:146. Review

A prospective evaluation of the temporal matrix metalloproteinase response after severe traumatic brain injury in humans.

Roberts DJ, Jenne CN, Léger C, Kramer AH, Gallagher CN, Todd S, Parney IF, Doig CJ, Yong VW, Kubes P, Zygun DA.

Reduced Brain/Serum Glucose Ratios Predict Cerebral Metabolic Distress and Mortality After Severe Brain Injury.

Kurtz P, Claassen J, Schmidt JM, Helbok R, Hanafy KA, Presciutti M, Lantigua H, Connolly ES, Lee K, Badjatia N, Mayer SA.
Neurocritical care. 2013 Oct 1.

Cerebral hemodynamic and metabolic effects of remote ischemic preconditioning in patients with subarachnoid hemorrhage.

Gonzalez NR, Hamilton R, Bilgin-Freiert A, Dusick J, Vespa P, Hu X, Asgari S.
Acta neurochirurgica. Supplement. 2013;115:193-8. doi: 10.1007/978-3-7091-1192-5_36.

Cerebral Microdialysis in Traumatic Brain Injury and Subarachnoid Hemorrhage: State of the Art.

de Lima Oliveira M, Kairalla AC, Fonoff ET, Martinez RC, Teixeira MJ, Bor-Seng-Shu E.
Neurocritical care. 2013 Sep 26

Techniques and strategies in neurocritical care originating from Southern Scandinavia.

Nordström CH, Nielsen TH, Jacobsen A.
Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine. 2013 Sep 3

Lactate uptake by the injured human brain – evidence from an arterio-venous gradient and cerebral microdialysis study.

Jalloh I, Helmy A, Shannon RJ, Gallagher CN, Menon D, Carpenter K, Hutchinson P.
Journal of neurotrauma. 2013 Aug 22

Cerebral extracellular lactate increase is predominantly nonischemic in patients with severe traumatic brain injury.

Sala N, Suys T, Zerlauth JB, Bouzat P, Messerer M, Bloch J, Levivier M, Magistretti PJ, Meuli R, Oddo M.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2013 Aug 21

The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury.

Skoglund K, Hillered L, Purins K, Tsitsopoulos PP, Flygt J, Engquist H, Lewén A, Enblad P, Marklund N.
Neurocritical care. 2013 Aug 10

Bedside Diagnosis of Mitochondrial Dysfunction After Malignant Middle Cerebral Artery Infarction.

Nielsen TH, Schalén W, Ståhl N, Toft P, Reinstrup P, Nordström CH.
Neurocritical care. 2013 Jul 17

Neuromonitoring with microdialysis in severe traumatic brain injury patients.

Sanchez JJ, Bidot CJ, O’Phelan K, Gajavelli S, Yokobori S, Olvey S, Jagid J, Garcia JA, Nemeth Z, Bullock R. Acta neurochirurgica. Supplement. 2013

Beyond intracranial pressure: optimization of cerebral blood flow, oxygen, and substrate delivery after traumatic brain injury.

Bouzat P, Sala N, Payen JF, Oddo M. Annals of intensive care. 2013 Jul

Monitoring of β-Amyloid Dynamics after Human Traumatic Brain Injury.

Marklund N, Farrokhnia N, Hånell A, Vanmechelen E, Enblad P, Zetterberg H, Blennow K, Hillered L.
ournal of neurotrauma. 2013 Jul 7.

Microdialysis study of cefotaxime cerebral distribution in patients with acute brain injury.

Dahyot-Fizelier C, Frasca D, Grégoire N, Adier C, Mimoz O, Debaene B, Couet W, Marchand S.
Antimicrobial agents and chemotherapy. 2013 Jun;57(6):2738-42. doi: 10.1128/AAC.02570-12. Epub 2013 Apr 9

Microdialysis monitoring of a craniofacial microvascular free flap reconstruction detected critical brain swelling.

Allen WN, King A, Blackburn TK.
Br J Neurosurg. 2013 May 25. [Epub ahead of print]

Continuous online microdialysis using microfluidic sensors: dynamic neuro-metabolic changes during spreading depolarisation.

Rogers ML, Feuerstein D, Leong CL, Takagaki M, Niu X, Graf R, Boutelle MG.
ACS chemical neuroscience. 2013 Apr 10.

Microdialysis Study of Cefotaxime Cerebral Distribution in Patients with Acute Brain Injury.

Dahyot-Fizelier C, Frasca D, Grégoire N, Adier C, Mimoz O, Debaene B, Couet W, Marchand S.
Antimicrobial agents and chemotherapy. 2013 Jun;57(6):2738-2742. Epub 2013 Apr 9

Exposure of Cyclosporin A in Whole Blood, Cerebral Spinal Fluid and Brain Extracellular Fluid Dialysate in Adults with Traumatic Brain Injury.

Brophy GM, Mazzeo AT, Brar S, Bunnell K, Gilman C, Karnes HT, Hayes RL, Bullock R.
Journal of neurotrauma. 2013 Mar 29.

Cerebral energy metabolism during mitochondrial dysfunction induced by cyanide in piglets.

Nielsen TH, Olsen NV, Toft P, Nordström CH.
Acta anaesthesiologica Scandinavica. 2013 Mar 18. doi: 10.1111/aas.12092

Invasive and noninvasive multimodal bedside monitoring in subarachnoid hemorrhage: a review of techniques and available data.

Arshi B, Mack WJ, Emanuel B.
Neurology research international. 2013;2013:987934. doi: 10.1155/2013/987934. Epub 2013 Mar 31

Cerebral microdialysis in clinical studies of drugs: pharmacokinetic applications.

Shannon RJ, Carpenter KL, Guilfoyle MR, Helmy A, Hutchinson PJ.
Journal of pharmacokinetics and pharmacodynamics. 2013 Mar 7.

Haemoglobin management in acute brain injury.

Leroux P.
Current opinion in critical care. 2013 Feb 3.

A neuropharmacokinetic assessment of bafetinib, a second generation dual BCR-Abl/Lyn tyrosine kinase inhibitor, in patients with recurrent high-grade gliomas.

Portnow J, Badie B, Markel S, Liu A, D’Apuzzo M, Frankel P, Jandial R, Synold TW.
European journal of cancer (Oxford, England : 1990). 2013 Feb 1. doi:pii: S0959-8049(13)00005-1. 10.1016/j.ejca.2013.01.001

Clusters of Spreading Depolarizations Are Associated With Disturbed Cerebral Metabolism in Patients With Aneurysmal Subarachnoid Hemorrhage.

Sakowitz OW, Santos E, Nagel A, Krajewski KL, Hertle DN, Vajkoczy P, Dreier JP, Unterberg AW, Sarrafzadeh AS Stroke; a journal of cerebral circulation. 2013 Jan;44(1):220-3. doi: 10.1161/STROKEAHA.112.672352.

Is cerebral microdialysis a clinical tool?

Helmy A, Hutchinson P.
Acta neurochirurgica. 2013 Feb;155(2):355-6. doi: 10.1007/s00701-012-1588-6. Epub 2012 Dec 21

Extracellular brain pH with or without hypoxia is a marker of profound metabolic derangement and increased mortality after traumatic brain injury.

Timofeev I, Nortje J, Al-Rawi PG, Hutchinson PJ, Gupta AK.

A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury.

James ML, Olson DM, Graffagnino C.
Anaesthesia and intensive care. 2012 Nov;40(6):949-57

Cerebral hemodynamic and metabolic effects of remote ischemic preconditioning in patients with subarachnoid hemorrhage.

Gonzalez NR, Hamilton R, Bilgin-Freiert A, Dusick J, Vespa P, Hu X, Asgari S.
Acta neurochirurgica. Supplement. 2013;115:193-8.PMID:22890668

Changes in cerebral oxidative metabolism in patients with acute liver failure.

Bjerring PN, Larsen FS.
Metabolic brain disease. 2012 Oct 26

Cerebral energy metabolism during induced mitochondrial dysfunction.

Nielsen TH, Bindslev TT, Pedersen SM, Toft P, Olsen NV, Nordström CH.
Acta anaesthesiologica Scandinavica. 2013 Feb;57(2):229-35. doi: 10.1111/j.1399-6576.2012.02783.x. Epub 2012 Sep 28.

New approaches to bedside monitoring in stroke.

Cyrous A, O’Neal B, Freeman WD.
Expert review of neurotherapeutics. 2012 Aug;12(8):915-28

Simulations and visualizations for interpretation of brain microdialysis data during deep brain stimulation.

Diczfalusy E, Dizdar N, Zsigmond P, Kullman A, Loyd D, Wardell K.
Conference proceedings : … Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2012 Aug

Cerebral hemodynamic and metabolic effects of remote ischemic preconditioning in patients with subarachnoid hemorrhage.

Gonzalez NR, Hamilton R, Bilgin-Freiert A, Dusick J, Vespa P, Hu X, Asgari S.
Acta neurochirurgica. Supplement. 2013;115:193-8.

Cerebral glucose and spreading depolarization in patients with aneurysmal subarachnoid hemorrhage.

Sarrafzadeh A, Santos E, Wiesenthal D, Martus P, Vajkoczy P, Oehmchen M, Unterberg A, Dreier JP, Sakowitz O

Tight glycemic control increases metabolic distress in traumatic brain injury: A randomized controlled within-subjects trial*.

Vespa P, McArthur DL, Stein N, Huang SC, Shao W, Filippou M, Etchepare M, Glenn T, Hovda DA.
Critical care medicine. 2012 Jun;40(6):1923-9

Relationship between systemic glucose and cerebral glucose is preserved in patients with severe traumatic brain injury, but glucose delivery to the brain may become limited when oxidative metabolism is impaired: implications for glycemic control.

Magnoni S, Tedesco C, Carbonara M, Pluderi M, Colombo A, Stocchetti N.
Critical care medicine. 2012 Jun;40(6):1785-91

The effects of continuous prostacyclin infusion on regional blood flow and cerebral vasospasm following subarachnoid haemorrhage: study protocol for a randomised controlled trial.

Rasmussen R, Wetterslev J, Stavngaard T, Skjøth-Rasmussen J, Grände PO, Olsen NV, Romner B.
Trials. 2012 Jul 2;13:102. doi: 10.1186/1745-6215-13-102

Implementation of cerebral microdialysis at a community-based hospital: A 5-year retrospective analysis.

Chen JW, Rogers SL, Gombart ZJ, Adler DE, Cecil S. Surgical neurology international. 2012;3:57.

Neuromonitoring after major neurosurgical procedures.

Messerer M, Daniel R, Oddo M. Minerva anestesiologica. 2012 May 4.

Brain multimodality monitoring: an update.

Oddo M, Villa F, Citerio G. Current opinion in critical care. 2012 Apr;18(2):111-8.

Cerebral Microdialysis Effects of Propofol versus Midazolam in Severe Traumatic Brain Injury.

Tanguy M, Seguin P, Laviolle B, Bleichner JP, Morandi X, Malledant Y.
Journal of neurotrauma. 2012 Apr 10;29(6):1105-10.

A microdialysis study of oral vigabatrin administration in head injury patients: preliminary evaluation of multimodality monitoring.

Carpenter KL, Timofeev I, Nortje J, Czosnyka M, Pickard JD, Hutchinson PJ. Acta neurochirurgica. Supplement. 2012;114:271-6

Matrix metalloproteinase-9 concentration in the cerebral extracellular fluid of patients during the acute phase of aneurismal subarachnoid hemorrhage.

Sarrafzadeh A, Copin JC, Bengualid DJ, Turck N, Vajkoczy P, Bijlenga P, Schaller K, Gasche Y.
Neurological research. 2012 Mar 20.

Brain Lactate Metabolism in Humans With Subarachnoid Hemorrhage.

Oddo M, Levine JM, Frangos S, Maloney-Wilensky E, Carrera E, Daniel RT, Levivier M, Magistretti PJ, Leroux PD. Stroke; a journal of cerebral circulation. 2012 Feb 16.

Penetration of doripenem in human brain: an observational microdialysis study in patients with acute brain injury.

Poeppl W, Zeitlinger M, Donath O, Wurm G, Müller M, Botha F, Illievich UM, Burgmann H.
International journal of antimicrobial agents. 2012 Feb 8.

Brain multimodality monitoring: an update.

Oddo M, Villa F, Citerio G. Current opinion in critical care. 2012 Feb 8.

Increase in cerebral metabolites during induction of propofol anaesthesia.

Bossers SM, Peerdeman SM, Oedayrajsingh Varma P, Baayen JC, De Witt Hamer PC, Schauer A, Loer SA, Boer C. British journal of anaesthesia. 2012 Jan;108(1):165-7.

Nutritional support and brain tissue glucose metabolism in poor-grade SAH: a retrospective observational study.

Schmidt JM, Claassen J, Ko SB, Lantiqua H, Presciutti M, Lee K, Connolly ES, Mayer SA, Seres DS, Badjatia N. Critical care (London, England). 2012 Jan 25;16(1):R15.

The cerebral extracellular release of glycerol, glutamate, and FGF2 is increased in older patients following severe traumatic brain injury.

Mellergård P, Sjögren F, Hillman J. Journal of neurotrauma. 2012 Jan 1;29(1):112-8.

Cerebral perfusion pressure, microdialysis biochemistry and clinical outcome in patients with traumatic brain injury.

Paraforou T, Paterakis K, Fountas K, Paraforos G, Chovas A, Tasiou A, Mpakopoulou M, Papadopoulos D, Karavellis A, Komnos A. BMC research notes. 2011 Dec 14;4:540

Cerebral microdialysis effects of propofol vs midazolam in severe traumatic brain injury [NCT 00336882].

Michele T, Philippe S, Bruno L, Jean-Paul B, Xavier M, Yannick M.
Journal of neurotrauma. 2011 Dec 19.

Neuro-inflammatory sequelae of minimal trauma in the non-traumatized human brain. A microdialysis study.

Bouras TI, Gatzonis SS, Georgakoulias N, Karatza M, Sianouni A, Stranjalis G, Boviatsis E, Vasileiou S, Sakas DE.Journal of neurotrauma. 2011 Nov 18.

Time course of recovery from cerebral vulnerability after severe traumatic brain injury: a microdialysis study.

Yokobori S, Watanabe A, Matsumoto G, Onda H, Masuno T, Fuse A, Kushimoto S, Yokota H.
The Journal of trauma. 2011 Nov;71(5):1235-40

Modified Lund concept versus cerebral perfusion pressure-targeted therapy: A randomised controlled study in patients with secondary brain ischaemia.

Dizdarevic K, Hamdan A, Omerhodzic I, Kominlija-Smajic E.
Clinical neurology and neurosurgery. 2011 Oct 28.

Elevated Intracranial Pressure, Low Cerebral Perfusion Pressure, and Impaired Brain Metabolism Correlate with Fatal Outcome after Severe Brain Injury.

Hejčl A, Bolcha M, Procházka J, Hušková E, Sameš M. Central European neurosurgery”>Cen Eur Neurosurg. 2011 Oct 17.

The Prognostic Value of Brain Extracellular Fluid Nitric Oxide Metabolites After Traumatic Brain Injury.

Tisdall MM, Rejdak K, Kitchen ND, Smith M, Petzold A.
Neurocritical care. 2011 Oct 15.

The Cerebral Extracellular Release of Glycerol, Glutamate, and FGF2 Is Increased in Older Patients following Severe Traumatic Brain Injury.

Mellergård P, Sjögren F, Hillman J.
Journal of neurotrauma. 2011 Oct 11.

Lack of consistent intracranial pressure pulse morphological changes during episodes of microdialysis lactate/pyruvate ratio increase.

Asgari S, Vespa P, Bergsneider M, Hu X.
Physiological measurement”>Physiol Meas. 2011 Oct;32(10):1639-51. Epub 2011 Sep 9

Detection of cerebral compromise with multimodality monitoring in patients with subarachnoid hemorrhage.

Chen HI, Stiefel MF, Oddo M, Milby AH, Maloney-Wilensky E, Frangos S, Levine JM, Kofke WA, LeRoux PD. Neurosurgery. 2011 Jul;69(1):53-63; discussion 63

Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue.

Reinstrup P, Nordström CH.
Neurocritical care. 2011 Jun;14(3):441-6.

Intracerebral monitoring of silent infarcts after subarachnoid hemorrhage.

Helbok R, Madineni RC, Schmidt MJ, Kurtz P, Fernandez L, Ko SB, Choi A, Stuart MR, Connolly ES, Lee K, Badjatia N, Mayer SA, Khandji AG, Claassen J.
Neurocrit Care. 2011 Apr;14(2):162-7.

Critical care of poor-grade subarachnoid hemorrhage.

Wartenberg KE.
Curr Opin Crit Care. 2011 Apr;17(2):85-93.

Alterations in cerebral oxidative metabolism following traumatic brain injury.

De Fazio M, Rammo R, O’Phelan K, Bullock MR.
Neurocrit Care. 2011 Feb;14(1):91-6.

Relation between brain interstitial and systemic glucose concentrations after subarachnoid hemorrhage.

Zetterling M, Hillered L, Enblad P, Karlsson T, Ronne-Engström E.
J Neurosurg. 2011 Apr 8. [Epub ahead of print]

Cerebral Perfusion Pressure Thresholds for Brain Tissue Hypoxia and Metabolic Crisis After Poor-Grade Subarachnoid Hemorrhage.

Schmidt JM, Ko SB, Helbok R, Kurtz P, Stuart RM, Presciutti M, Fernandez L, Lee K, Badjatia N, Connolly ES, Claassen J, Mayer SA.
Stroke. 2011 Mar 24. [Epub ahead of print]

Analyses of cerebral microdialysis in patients with traumatic brain injury: relations to intracranial pressure, cerebral perfusion pressure and catheter placement.

Nelson DW, Thornquist B, Maccallum RM, Nyström H, Holst A, Rudehill A, Wanecek M, Bellander BM, Weitzberg E.
BMC Med. 2011 Mar 2;9:21.

Potential Non-Hypoxic/Ischemic Causes of Increased Cerebral Interstitial Fluid Lactate/Pyruvate Ratio: A Review of Available Literature.

Larach DB, Kofke WA, Le Roux P.
Neurocrit Care. 2011 Feb 19. [Epub ahead of print]

Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome-c-Oxidase in Traumatic Brain Injury Patients during Hypercapnoea : A Broadband NIRS Study.

Tachtsidis I, Tisdall MM, Pritchard C, Leung TS, Ghosh A, Elwell CE, Smith M.
Adv Exp Med Biol. 2011;915:9-14

Differences in cerebral extracellular response of interleukin-1?, interleukin-6, and interleukin-10 after subarachnoid hemorrhage or severe head trauma in humans.

Mellergård P, Åneman O, Sjögren F, Säberg C, Hillman J. Neurosurgery. 2011 Jan;68(1):12-9; discussion

In vivo monitoring of neuronal loss in traumatic brain injury: a microdialysis study.

Petzold A, Tisdall MM, Girbes AR, Martinian L, Thom M, Kitchen N, Smith M.
Brain. 2011 Feb;134(Pt 2):464-83.

Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients.

Timofeev I, Carpenter KL, Nortje J, Al-Rawi PG, O’Connell MT, Czosnyka M, Smielewski P, Pickard JD, Menon DK, Kirkpatrick PJ, Gupta AK, Hutchinson PJ.
Brain. 2011 Feb;134(Pt 2):484-94. Epub 2011 Jan 18.

The cytokine response to human traumatic brain injury: temporal profiles and evidence for cerebral parenchymal production.

Helmy A, Carpenter KL, Menon DK, Pickard JD, Hutchinson PJ.
J Cereb Blood Flow Metab. 2011 Feb;31(2):658-70. Epub 2010 Aug 18

New modalities to assess efficacy of triple-h therapy: early experience.

Bhargava D, Al-Tamimi Y, Quinn A, Ross S.
Acta Neurochir Suppl. 2011;110(Pt 2):203-7

Cerebral microdialysis: perioperative monitoring and treatment of severe neurosurgical patient.

Omerhodzić I, Dizdarević K, Rotim K, Hajdarpasić E, Niksić M, Bejtić-Custović E, Selimović E, Custović M.
Acta clinica Croatica. 2011 Mar;50(1):13-20

Lack of correlation among intracerebral cytokines, intracranial pressure, and brain tissue oxygenation in patients with traumatic brain injury and diffuse lesions.

Perez-Barcena J, Ibáñez J, Brell M, Crespí C, Frontera G, Llompart-Pou JA, Homar J, Abadal JM.
Crit Care Med. 2011 Mar;39(3):533-40

New modalities to assess efficacy of triple-h therapy: early experience.

Bhargava D, Al-Tamimi Y, Quinn A, Ross S.
Acta Neurochir Suppl. 2011;110(Pt 2):203-7

Hypoperfusion in the acute phase of subarachnoid hemorrhage.

Schubert GA, Seiz M, Hegewald AA, Manville J, Thomé C.
Acta Neurochir Suppl. 2011;110(Pt 1):35-8

Cerebral microdialysis in acutely brain-injured patients with spreading depolarizations.

Krajewski KL, Orakcioglu B, Haux D, Hertle DN, Santos E, Kiening KL, Unterberg AW, Sakowitz OW.
Acta Neurochir Suppl. 2011;110(Pt 1):125-30

Decompressive craniectomy guided by cerebral microdialysis and brain tissue oxygenation in a patient with meningitis.

Bordes J, Boret H, Lacroix G, Prunet B, Meaudre E, Kaiser E.
Acta Anaesthesiol Scand. 2011 Jan;55(1):130-3. doi: 10.1111/j.1399-6576.2010.02355.x.

Clinical microdialysis in neuro-oncology: principles and applications.

Goodman JC. Chin J Cancer. 2011 Mar;30(3):173-81.

Cerebral extracellular chemistry and outcome following traumatic brain injury

Ivan Timofeev, Keri L. H. Carpenter, Ju¨ rgens Nortje, Pippa G. Al-Rawi, Mark T. O’Connell,Marek Czosnyka, Peter Smielewski, John D. Pickard, David K. Menon, Peter J. Kirkpatrick, Arun K. Gupta and Peter J. Hutchinson Brain, 2011 January: 134; 484–494

Hyperglycemia in aneurysmal subarachnoid hemorrhage: a potentially modifiable risk factor for poor outcome.

Kruyt ND, Biessels GJ, DeVries JH, Luitse MJ, Vermeulen M, Rinkel GJ, Vandertop WP, Roos YB.
J Cereb Blood Flow Metab. 2010 Sep;30(9):1577-87. Epub 2010 Jul 14

Effect of mannitol on brain metabolism and tissue oxygenation in severe haemorrhagic stroke.

Helbok R, Kurtz P, Schmidt JM, Stuart RM, Fernandez L, Malhotra R, Presciutti M, Ostapkovich ND, Connolly ES, Lee K, Badjatia N, Mayer SA, Claassen J.
J Neurol Neurosurg Psychiatry. 2010 Sep 30. [Epub ahead of print]

Role of extracellular glutamate measured by cerebral microdialysis in severe traumatic brain injury.

Chamoun R, Suki D, Gopinath SP, Goodman JC, Robertson C.
J Neurosurg. 2010 Sep;113(3):564-70

Anemia is associated with metabolic distress and brain tissue hypoxia after subarachnoid hemorrhage.

Kurtz P, Schmidt JM, Claassen J, Carrera E, Fernandez L, Helbok R, Presciutti M, Stuart RM, Connolly ES, Badjatia N, Mayer SA,Lee K.
Neurocrit Care. 2010 Aug;13(1):10-6.

Change in brain glucose after enteral nutrition in subarachnoid hemorrhage.

Kinoshita K, Moriya T, Utagawa A, Sakurai A, Mukoyama T, Furukawa M, Yamaguchi J, Tanjoh K.
J Surg Res. 2010 Aug;162(2):221-4. Epub 2009 Sep 22.

Is lactate a good indicator of brain tissue hypoxia in the acute phase of traumatic brain injury? Results of a pilot study in 21 patients [Article in Spanish]

Merino MA, Sahuquillo J, Borrull A, Poca MA, Riveiro M, Expósito L.
Neurocirugia (Astur). 2010 Aug;21(4):289-301.

The cytokine response to human traumatic brain injury: temporal profiles and evidence for cerebral parenchymal production.

Helmy A, Carpenter KL, Menon DK, Pickard JD, Hutchinson PJ.
J Cereb Blood Flow Metab. 2010 Aug 18. [Epub ahead of print]

Brain hypoxanthine concentration correlates to lactate/pyruvate ratio but not intracranial pressure in patients with acute liver failure.

Bjerring PN, Hauerberg J, Jørgensen L, Frederiksen HJ, Tofteng F, Hansen BA, Larsen FS.
J Hepatol. 2010 Aug 3. [Epub ahead of print]

Dynamic metabolic response to multiple spreading depolarizations in patients with acute brain injury: an online microdialysis study.

Feuerstein D, Manning A, Hashemi P, Bhatia R, Fabricius M, Tolias C, Pahl C, Ervine M, Strong AJ, Boutelle MG.
J Cereb Blood Flow Metab. 2010 Jul;30(7):1343-55. Epub 2010 Feb 10.

Metabolic crisis after traumatic brain injury is associated with a novel microdialysis proteome.

Lakshmanan R, Loo JA, Drake T, Leblanc J, Ytterberg AJ, McArthur DL, Etchepare M, Vespa PM.
Neurocrit Care. 2010 Jun;12(3):324-36

Methodological aspects on microdialysis protein sampling and quantification in biological fluids: an in vitro study on human ventricular CSF.

Correlation between brain interstitial and total serum cortisol levels in traumatic brain injury. A preliminary study.

Llompart-Pou JA, Pérez G, Pérez-Bárcena J, Brell M, Ibáñez J, Riesco M, Abadal JM, Homar J, Marsé P, Ibáñez J, Burguera B,Raurich JM. J Endocrinol Invest. 2010 Jun;33(6):368-72

Traumatic Brain Injury: Advanced Multimodal Neuromonitoring From Theory to Clinical Practice. Cecil S, Chen PM, Callaway SE, Rowland SM, Adler

DE, Chen JW.
Crit Care Nurse. 2010 Jun 30. [Epub ahead of print]

Release of VEGF and FGF in the extracellular space following severe subarachnoidal haemorrhage or traumatic head injury in humans.

Mellergård P, Sjögren F, Hillman J. Br J Neurosurg. 2010 Jun;24(3):261-7

Intracerebral microdialysis during deep brain stimulation surgery.

Kilpatrick M, Church E, Danish S, Stiefel M, Jaggi J, Halpern C, Kerr M, Maloney E, Robinson M, Lucki I, Krizman-Grenda E, Baltuch G. J Neurosci Methods. 2010 Jun 30;190(1):106-11. Epub 2010 Apr 21

Microdialysis-based sensing in clinical applications.

Baldini F. Anal Bioanal Chem. 2010 Jun;397(3):909-16. Epub 2010 Mar 17

Intra-operative, real-time, three-dimensional ultrasound assisted positioning of catheters in the microdialysis of glial tumours.

Homapour B, Bowen JE, Want EJ, O’Neill K, Apostolopoulos V, Nandi D, Van Dellen JR, Roncaroli F.
J Clin Neurosci. 2010 Apr;17(4):506-10. Epub 2010 Jan 21

A prospective, randomized clinical trial to compare the effect of hyperbaric to normobaric hyperoxia on cerebral metabolism, intracranial pressure, and oxygen toxicity in severe traumatic brain injury.

Rockswold SB, Rockswold GL, Zaun DA, Zhang X, Cerra CE, Bergman TA, Liu J.
J Neurosurg. 2010 May;112(5):1080-94.

Metabolomic Patterns in Glioblastoma and Changes during Radiotherapy: A Clinical Microdialysis Study.

Wibom C, Surowiec I, Mörén L, Bergstro?m P, Johansson M, Antti H, Bergenheim AT.
J Proteome Res. 2010 Apr 22. [Epub ahead of print]

Cerebral energy metabolism and microdialysis in neurocritical care.

Nordström CH. Childs Nerv Syst.2010 Apr;26(4):465-72

Anemia is Associated with Metabolic Distress and Brain Tissue Hypoxia After Subarachnoid Hemorrhage.

Kurtz P, Schmidt JM, Claassen J, Carrera E, Fernandez L, Helbok R, Presciutti M, Stuart RM, Connolly ES, Badjatia N, Mayer SA, Lee K. Neurocrit Care. 2010 Apr 10. [Epub ahead of print]

Brain interstitial fluid TNF-alpha after subarachnoid hemorrhage.

Hanafy KA, Grobelny B, Fernandez L, Kurtz P, Connolly ES, Mayer SA, Schindler C, Badjatia N.
J Neurol Sci. 2010 Apr 15;291(1-2):69-73. Epub 2010 Jan 27

Metabolomic patterns in glioblastoma and changes during radiotherapy – a clinical microdialysis study.

Wibom C, Surowiec I, Mörén L, Bergström P, Johansson M, Antti H, Bergenheim T.
J Proteome Res. 2010 Mar 21. [Epub ahead of print]

Metabolic Crisis After Traumatic Brain Injury is Associated with a Novel Microdialysis Proteome.

Lakshmanan R, Loo JA, Drake T, Leblanc J, Ytterberg AJ, McArthur DL, Etchepare M, Vespa PM.
Neurocrit Care. 2010 Mar 12. [Epub ahead of print]

What has inflammation to do with traumatic brain injury?

Cederberg D, Siesjö P. Childs Nerv Syst. 2010 Feb;26(2):221-6. Epub 2009 Nov 26

Systemic Glucose and Brain Energy Metabolism after Subarachnoid Hemorrhage.

Helbok R, Schmidt JM, Kurtz P, Hanafy KA, Fernandez L, Stuart RM, Presciutti M, Ostapkovich ND, Connolly ES, Lee K, Badjatia N, Mayer SA, Claassen J. Neurocrit Care. 2010 Feb 5. [Epub ahead of print]

Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose beneath 1 mM in patients with severe traumatic brain injury.

Meierhans R, Bechir M, Ludwig S, Sommerfeld J, Brandi G, Haberthur C, Stocker R, Stover JF.
Crit Care. 2010 Feb 8;14(1):R13. [Epub ahead of print]

Dynamic metabolic response to multiple spreading depolarizations in patients with acute brain injury: an online microdialysis study.

Feuerstein D, Manning A, Hashemi P, Bhatia R, Fabricius M, Tolias C, Pahl C, Ervine M, Strong AJ, Boutelle MG. J Cereb Blood Flow Metab. 2010 Feb 10. [Epub ahead of print]

 

Imaging of hypoxic-ischemic penumbra with (18)F-fluoromisonidazole PET/CT and measurement of related cerebral metabolism in aneurysmal subarachnoid hemorrhage.
Sarrafzadeh AS, Nagel A, Czabanka M, Denecke T, Vajkoczy P, Plotkin M. J Cereb Blood Flow Metab. 2010 Jan;30(1):36-45. Epub 2009 Sep 23

Intracranial Multimodal Monitoring for Acute Brain Injury: A Single Institution Review of Current Practices.
Stuart RM, Schmidt M, Kurtz P, Waziri A, Helbok R, Mayer SA, Lee K, Badjatia N, Hirsch LJ, Connolly ES, Claassen J.
Neurocrit Care. 2010 Jan 27. [Epub ahead of print]

Clinical management and functional neuromonitoring in traumatic brain injury in children.

Guerguerian AM, Lo TY, Hutchison JS.
Curr Opin Pediatr. 2009 Dec;21(6):737-44. Review.

Relationship between intracranial hemodynamics and microdialysis markers of energy metabolism and glutamate-glutamine turnover in patients with subarachnoid hemorrhage. Clinical article.

Samuelsson C, Howells T, Kumlien E, Enblad P, Hillered L, Ronne-Engström E.
J Neurosurg. 2009 Nov;111(5):910-5.

Subarachnoid hemorrhage and microdialysis.

Macdonald RL.
J Neurosurg. 2009 Nov;111(5):907-8

Response.

Samuelsson C, Howells T, Kumlien E, Enblad P, Hillered L, Ronne-Engström E.
J Neurosurg. 2009 Nov;111(5):908-9. No abstract available

The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation.

Portnow J, Badie B, Chen M, Liu A, Blanchard S, Synold TW.
Clin Cancer Res. 2009 Nov 15;15(22):7092-8. Epub 2009 Oct 27

The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study.

Gallagher CN, Carpenter KL, Grice P, Howe DJ, Mason A, Timofeev I, Menon DK, Kirkpatrick PJ, Pickard JD, Sutherland GR, Hutchinson PJ.
Brain. 2009 Oct;132(Pt 10):2839-49. Epub 2009 Aug 20

Brain tissue lactate elevations predict episodes of intracranial hypertension in patients with traumatic brain injury.

Adamides AA, Rosenfeldt FL, Winter CD, Pratt NM, Tippett NJ, Lewis PM, Bailey MJ, Cooper DJ, Rosenfeld JV.
J Am Coll Surg. 2009 Oct;209(4):531-9. Epub 2009 Jul 9

The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study.

Gallagher CN, Carpenter KL, Grice P, Howe DJ, Mason A, Timofeev I, Menon DK, Kirkpatrick PJ, Pickard JD, Sutherland GR, Hutchinson PJ.
Brain. 2009 Aug 20. [Epub ahead of print]

In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines.

Marcus HJ, Carpenter KL, Price SJ, Hutchinson PJ.
J Neurooncol. 2009 Aug 28. [Epub ahead of print]

High ICP as trigger of proinflammatory IL-6 cytokine activation in aneurysmal subarachnoid hemorrhage.

Graetz D, Nagel A, Schlenk F, Sakowitz O, Vajkoczy P, Sarrafzadeh A.
Neurol Res. 2009 Aug 13. [Epub ahead of print]

Multimodality Neuromonitoring and Decompressive Hemicraniectomy After Subarachnoid Hemorrhage.

Morgan Stuart R, Claassen J, Schmidt M, Helbok R, Kurtz P, Fernandez L, Lee K, Badjatia N, Mayer SA, Lavine S, Sander Connolly E.
Neurocrit Care. 2009 Aug 8. [Epub ahead of print]

Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations.

Clinckers R, Smolders I, Vermoesen K, Michotte Y, Danhof M, Voskuyl R, Della Pasqua O.
Expert Opin Drug Metab Toxicol. 2009 Jul 17. [Epub ahead of print]

Neuromonitoring in intensive care: focus on microdialysis and its nursing implications.

Presciutti M, Schmidt JM, Alexander S.
J Neurosci Nurs. 2009 Jun;41(3):131-9. Review

Microdialysis patterns in subarachnoid hemorrhage patients with focus on ischemic events and brain interstitial glutamine levels.

Samuelsson C, Hillered L, Enblad P, Ronne-Engström E.
Acta Neurochir (Wien). 2009 May;151(5):437-46; discussion 446. Epub 2009 Mar 19

Microdialysis: is it ready for prime time?

Goodman JC, Robertson CS.
Curr Opin Crit Care. 2009 Apr;15(2):110-7

Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage.

Nagel A, Graetz D, Schink T, Frieler K, Sakowitz O, Vajkoczy P, Sarrafzadeh A.
J Neurosurg. 2009 Mar 13. [Epub ahead of print]

Intracerebral monitoring in comatose patients treated with hypothermia after a cardiac arrest.

Nordmark J, Rubertsson S, Mörtberg E, Nilsson P, Enblad P.
Acta Anaesthesiol Scand. 2009 Mar;53(3):289-98

Hemoglobin Concentration and Cerebral Metabolism in Patients With Aneurysmal Subarachnoid Hemorrhage.

Oddo M, Milby A, Chen I, Frangos S, Macmurtrie E, Maloney-Wilensky E, Stiefel M, Kofke WA, Levine JM, Le Roux PD.
Stroke; a journal of cerebral circulation. 2009 Mar 5. [Epub ahead of print]

Prostacylin Treatment in Severe Traumatic Brain Injury – a microdialysis and outcome study.
Olivecrona M, Rodling-Wahlström M, Naredi S, Koskinen LO.
J Neurotrauma. 2009 Feb 18. [Epub ahead of print]

Induced Normothermia Attenuates Cerebral Metabolic Distress in Patients With Aneurysmal Subarachnoid Hemorrhage and Refractory Fever.

Oddo M, Frangos S, Milby A, Chen I, Maloney-Wilensky E, Murtrie EM, Stiefel M, Kofke WA, Le Roux PD, Levine JM.
Stroke; a journal of cerebral circulation. 2009 Feb 26. [Epub ahead of print]

Microdialysis of Cytokines: Methodological Considerations, Scanning Electron Microscopy, and Determination of Relative Recovery.

Helmy A, Carpenter KL, Skepper JN, Kirkpatrick PJ, Pickard JD, Hutchinson PJ.
Journal of neurotrauma. 2009 Feb 5. [Epub ahead of print]

Monitoring of brain interstitial total tau and beta amyloid proteins by microdialysis in patients with traumatic brain injury.

Marklund N, Blennow K, Zetterberg H, Ronne-Engström E, Enblad P, Hillered L
J Neurosurg. 2009 Feb 13. [Epub ahead of print]

Pathogenesis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: putative mechanisms and novel approaches.

Kolias AG, Sen J, Belli A.
J Neurosci Res. 2009 Jan;87(1):1-11. Review

A combined microdialysis and FDG-PET study of glucose metabolism in head injury.

Hutchinson PJ, O’Connell MT, Seal A, Nortje J, Timofeev I, Al-Rawi PG, Coles JP, Fryer TD, Menon DK, Pickard JD, Carpenter KL.
Acta Neurochir (Wien). 2009 Jan;151(1):51-61; discussion 61. Epub 2008 Dec 20.

Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study.

Blakeley JO, Olson J, Grossman SA, He X, Weingart J, Supko JG; New Approaches to Brain Tumor Therapy (NABTT) Consortium.
J Neurooncol. 2009 Jan;91(1):51-8. Epub 2008 Sep 12.

Hartings JA, Gugliotta M, Gilman C, Strong AJ, Tortella FC, Bullock MR.

Repetitive cortical spreading depolarizations in a case of severe brain trauma
Neurol Res. 2008 Oct; 30 ( 8 ): 876-82

Hillered L, Enblad P.

Nonischemic energy metabolic crisis in acute brain injury.
Crit Care Med. 2008 Oct; 36 ( 10 ): 2952-3 . No abstract available

Marcoux J, McArthur DA, Miller C, Glenn TC, Villablanca P, Martin NA, Hovda DA, Alger JR, Vespa PM.

Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury
Crit Care Med. 2008 Oct; 36 ( 10 ): 2871-7

Mazzeo AT, Alves OL, Gilman CB, Hayes RL, Tolias C, Niki Kunene K, Ross Bullock M.

Brain metabolic and hemodynamic effects of cyclosporin A after human severe traumatic brain injury: a microdialysis study.
Acta Neurochir (Wien). 2008 Oct; 150 ( 10 ): 1019-31; discussion 1031 . Epub 2008 Sep

Oddo M, Schmidt JM, Carrera E, Badjatia N, Connolly ES, Presciutti M, Ostapkovich ND, Levine JM, Le Roux P, Mayer SA.

Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: A microdialysis study.
Crit Care Med. 2008 Oct 17. [Epub ahead of printSeptember 2008

Berger C, Kiening K, Schwab S.

Neurochemical Monitoring of Therapeutic Effects in Large Human MCA Infarction
Neurocrit Care. 2008; 9 ( 3 ): 352-6

Tisdall MM, Tachtsidis I, Leung TS, Elwell CE, Smith M.

Increase in cerebral aerobic metabolism by normobaric hyperoxia after traumatic brain injury.
J Neurosurg. 2008 Sep; 109 ( 3 ): 424-32 .

White H, Venkatesh B.

Cerebral perfusion pressure in neurotrauma: a review .
Anesth Analg. 2008 Sep; 107 ( 3 ): 979-88 . Review.

Brody DL, Magnoni S, Schwetye KE, Spinner ML, Esparza TJ, Stocchetti N, Zipfel GJ, Holtzman DM.

Amyloid-beta dynamics correlate with neurological status in the injured human brain
Science. 2008 Aug 29; 321 ( 5893 ): 1221-4 .

Cavus I, Pan JW, Hetherington HP, Abi-Saab W, Zaveri HP, Vives KP, Krystal JH, Spencer SS, Spencer DD.

Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients
Epilepsia. 2008 Aug; 49 ( 8 ): 1358-66 . Epub 2008 Apr 10

Lindvall P, Roslin M, Bergenheim AT.

Cerebral metabolism during air transport of patients after surgery for malignant glioma.
Aviat Space Environ Med. 2008 Jul; 79 ( 7 ): 700-3 .

Belli A, Sen J, Petzold A, Russo S, Kitchen N, Smith M.

Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study.
Acta Neurochir (Wien). 2008 May; 150 ( 5 ): 461-9;April 2008

Andrews PJ, Citerio G, Longhi L, Polderman K, Sahuquillo J, Vajkoczy P; Neuro-Intensive Care and Emergency Medicine (NICEM) Section of the European Society of Intensive Care Medicine.

NICEM consensus on neurological monitoring in acute neurological disease.
Intensive Care Med. 2008 Apr 9.

Berger C, Kiening K, Schwab S.

Neurochemical Monitoring of Therapeutic Effects in Large Human MCA Infarction .
Neurocrit Care. 2008 Apr 15

Cavus I, Pan JW, Hetherington HP, Abi-Saab W, Zaveri HP, Vives KP, Krystal JH, Spencer SS, Spencer DD.

Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients.
Epilepsia. 2008 Apr 10.

Diringer MN.

Hyperoxia: good or bad for the injured brain?
Curr Opin Crit Care. 2008 Apr; 14 ( 2 ): 167-71 .

Ho CL, Ang CB, Lee KK, Ng IH.

Effects of glycaemic control on cerebral neurochemistry in primary intracerebral haemorrhage
J Clin Neurosci. 2008 Apr; 15 ( 4 ): 428-33 . Epub 2008 Feb 6.

Li AL, Zhi DS, Wang Q, Huang HL.

Extracellular glycerol in patients with severe traumatic brain injury
Chin J Traumatol. 2008 Apr; 11 ( 2 ): 84-8

Schlenk F, Sarrafzadeh AS.

Is continuous insulin treatment safe in aneurysmal subarachnoid hemorrhage?
Vasc Health Risk Manag. 2008;4(4):885-91.

McAdoo DJ, Wu P.

Microdialysis in central nervous system disorders and their treatment.
Pharmacol Biochem Behav.2008 Mar 10.

Nordström CH.

Insulin, intracerebral glucose and bedside biochemical monitoring utilizing microdialysis.
Crit Care. 2008 Mar 31; 12 ( 2 ): 124 .

Petrikov SS, Solodov AA, Titova IuV, Krylov VV.

[The first experience with simultaneous bilateral monitoring of brain oxygenation and metabolism in patients with intracranial hemorrhages]
Anesteziol Reanimatol. 2008 Mar-Apr;( 2 ): 73-5 . RussianJanuary 2008

Mellergård P, Aneman O, Sjögren F, Pettersson P, Hillman J.

Changes in extracellular concentrations of some cytokines, chemokines, and neurotrophic factors after insertion of intracerebral microdialysis catheters in neurosurgical patients .
Neurosurgery. 2008 Jan; 62 ( 1 ): 151-7; discussion 157-8 .

Nortje J, Coles JP, Timofeev I, Fryer TD, Aigbirhio FI, Smielewski P, Outtrim JG, Chatfield DA, Pickard JD, Hutchinson PJ, Gupta AK, Menon DK.

Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings.
Critical care medicine. 2008 Jan;36(1):273-81.

Schlenk F, Graetz D, Nagel A, Schmidt M, Sarrafzadeh AS.

Insulin-related decrease in cerebral glucose despite normoglycemia in aneurysmal subarachnoid hemorrhage.
Crit Care. 2008 Jan 24;12(1):R9

Vespa PM, Miller C, McArthur D, Eliseo M, Etchepare M, Hirt D, Glenn TC, Martin N, Hovda D.

Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis.
Crit Care Med. 2007 Dec;35(12):2830-6.

Springborg JB, Møller C, Gideon P, Jørgensen OS, Juhler M, Olsen NV.

Erythropoietin in patients with aneurysmal subarachnoid haemorrhage: a double blind randomised clinical trial.
Acta Neurochir (Wien). 2007 Nov;149(11):1089-101; discussion 1101. Epub 2007 Sep 17.

Hutchinson PJ, O’Connell MT, Rothwell NJ, Hopkins SJ, Nortje J, Carpenter KL, Timofeev I, Al-Rawi PG, Menon DK, Pickard JD.

Inflammation in Human Brain Injury: Intracerebral Concentrations of IL-1alpha, IL-1beta, and Their Endogenous Inhibitor IL-1ra.
J Neurotrauma . 2007 Oct;24(10):1545-57.

Maurer MH, Haux D, Sakowitz OW, Unterberg AW, Kuschinsky W.

Identification of early markers for symptomatic vasospasm in human cerebral microdialysate after subarachnoid hemorrhage: preliminary results of a proteome-wide screening.
J Cereb Blood Flow Metab . 2007 Oct;27(10):1675-83.

Wright WL.

Multimodal monitoring in the ICU: when could it be useful?
J Neurol Sci. 2007 Oct 15;261(1-2):10-5. Review.

Upton RN.

Cerebral uptake of drugs in humans .
Clin Exp Pharmacol Physiol . 2007 Aug;34(8):695-701. Review.

Hlatky R, Valadka AB, Goodman JC, Robertson CS.

Evolution of brain tissue injury after evacuation of acute traumatic subdural hematomas
Neurosurgery. 2007 Jul; 61 ( 1 Suppl ): 249-54; discussion 254-5

Meybohm P, Cavus E, Bein B, Steinfath M, Weber B, Scholz J, Doerges V.

Neurochemical monitoring using intracerebral microdialysis during systemic haemorrhage.
Acta Neurochir (Wien) . 2007 Jul;149(7):691-8.

Reinert M, Andres RH, Fuhrer M, Müller A, Schaller B, Widmer H.

Online correlation of spontaneous arterial and intracranial pressure fluctuations in patients with diffuse severe head injury.
Neurol Res. 2007 Jul;29(5):455-62.

Samuelsson C, Hillered L, Zetterling M, Enblad P, Hesselager G, Ryttlefors M, Kumlien E, Lewen A, Marklund N, Nilsson P, Salci K, Ronne-Engstrom E.

Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients.
J Cereb Blood Flow Metab . 2007 Jul;27(7):1309-17.

Wartenberg KE, Schmidt JM, Mayer SA.

Multimodality monitoring in neurocritical care.
Crit Care Clin. 2007 Jul;23(3):507-38. Review

Helmy A, Carpenter KL, Hutchinson PJ.

Microdialysis in the human brain and its potential role in the development and clinical assessment of drugs.
Curr Med Chem. 2007;14(14):1525-37.

Hillman J, Aneman O, Persson M, Andersson C, Dabrosin C, Mellergård P.

Variations in the response of interleukins in neurosurgical intensive care patients monitored using intracerebral microdialysis .
J Neurosurg. 2007 May; 106 ( 5 ): 820-5 .

Flannery T, McConnell RS, McQuaid S, McGregor G, Mirakhur M, Martin L, Scott C, Burden R, Walker B, McGoohan C, Johnston PG.

Detection of cathepsin S cysteine protease in human brain tumour microdialysates in vivo.
Br J Neurosurg . 2007 Apr;21(2):204-9.

Poca MA, Sahuquillo J, Vilalta A, Garnacho A.

Lack of utility of arteriojugular venous differences of lactate as a reliable indicator of increased brain anaerobic metabolism in traumatic brain injury.
J Neurosurg . 2007 Apr;106(4):530-7.

Rincon F, Mayer SA.

Neurocritical care: a distinct discipline?
Curr Opin Crit Care. 2007 Apr;13(2):115-21. Review.

Vespa PM, O’Phelan K, McArthur D, Miller C, Eliseo M, Hirt D, Glenn T, Hovda DA.

Pericontusional brain tissue exhibits persistent elevation of lactate/pyruvate ratio independent of cerebral perfusion pressure.
Crit Care Med. 2007 Apr;35(4):1153-60.

Sakowitz OW, Stover JF, Sarrafzadeh AS, Unterberg AW, Kiening KL.

Effects of mannitol bolus administration on intracranial pressure, cerebral extracellular metabolites, and tissue oxygenation in severely head-injured patients.
J Trauma. 2007 Feb;62(2):292-8.

Dohmen C, Bosche B, Graf R, Reithmeier T, Ernestus RI, Brinker G, Sobesky J, Heiss WD.

Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction.
Stroke. 2007 Jan;38(1):56-61.

Miller CM, Vespa PM, McArthur DL, Hirt D, Etchepare M.

Frameless stereotactic aspiration and thrombolysis of deep intracerebral hemorrhage is associated with reduced levels of extracellular cerebral glutamate and unchanged lactate pyruvate ratios.
Neurocrit Care. 2007;6(1):22-9.

Brunner M, Langer O.

Microdialysis versus other techniques for the clinical assessment of in vivo tissue drug distribution.
AAPS J. 2006 Apr 14;8(2):E263-71. Review.

Hocht C, Opezzo JA, Taira CA.

Applicability of reverse microdialysis in pharmacological and toxicological studies.
J Pharmacol Toxicol Methods. 2006 Mar 6;

Nicolazzo JA, Charman SA, Charman WN.

Methods to assess drug permeability across the blood-brain barrier.
J Pharm Pharmacol. 2006 Mar;58(3):281-93. Review.

Tisdall MM, Smith M.

Cerebral microdialysis: research technique or clinical tool.
Br J Anaesth. 2006 Jul;97(1):18-25. Review

Bergenheim AT, Roslin M, Ungerstedt U, Waldenstrom A, Henriksson R, Ronquist G.

Metabolic Manipulation of Glioblastoma in Vivo by Retrograde Microdialysis of L-2, 4 Diaminobutyric Acid (DAB).
J Neurooncol. 2006 Dec;80(3):285-93. Epub 2006 Jun 14.

Berg A , Bellander BM , Wanecek M , Gamrin L , Elving A , Rooyackers O , Ungerstedt U , Wernerman J

Intravenous glutamine supplementation to head trauma patients leaves cerebral glutamate concentration unaffected.
Intensive Care Med. 2006 Nov;

De Deyne CS, Struys MR.

New developments in cerebral monitoring.
Curr Opin Anaesthesiol. 2000 Oct;13(5):517-21.

Morris KP , Forsyth RJ , Parslow RC , Tasker RC , Hawley CA ; UK Paediatric Traumatic Brain Injury Study Group ; Paediatric Intensive Care Society Study Group

Intracranial pressure complicating severe traumatic brain injury in children: monitoring and management.
Intensive Care Med. 2006 Oct;32(10):1606-1612. Epub 2006 Jul 28.

Poca MA , Sahuquillo J , Vilalta A , de los Rios J , Robles A , Exposito L .

Percutaneous implantation of cerebral microdialysis catheters by twist-drill craniostomy in neurocritical patients: description of the technique and results of a feasibility study in 97 patients.
J Neurotrauma . 2006 Oct;23(10):1510-7.

Tisdall M , Russo S , Sen J , Belli A , Ratnaraj N , Patsalos P , Petzold A , Kitchen N , Smith M .

Free phenytoin concentration measurement in brain extracellular fluid: a pilot study.
Br J Neurosurg. 2006 Oct;20(5):285-9.

Berg A, Bellander BM, Wanecek M, Gamrin L, Elving A, Rooyackers O, Ungerstedt U, Wernerman J.

Intravenous glutamine supplementation to head trauma patients leaves cerebral glutamate concentration unaffected.
Intensive Care Med. 2006 Sep 23;

Nilsson OG, Polito A, Saveland H, Ungerstedt U, Nordstrom CH.

Are primary supratentorial intracerebral hemorrhages surrounded by a biochemical penumbra? A microdialysis study.
Neurosurgery. 2006 Sep;59(3):521-8; discussion 521-8.

Daboussi A, Fourcade O.

[Cerebral ischemic threshold in clinical practice]
Ann Fr Anesth Reanim. 2006 Jul;25(7):729-34.

Engstrom M, Schott U, Nordstrom CH, Romner B, Reinstrup P.

Increased lactate levels impair the coagulation system–a potential contributing factor to progressive hemorrhage after traumatic brain injury.
J Neurosurg Anesthesiol. 2006 Jul;18(3):200-4.

Joly LM, Mertes PM.

[Monitoring of cerebral oxygenation with SvjO(2) or PtiO(2)]
Ann Fr Anesth Reanim. 2006 Jul;25(7):748-54. Epub 2006 Jul 3. French.

Mazzeo AT, Kunene NK, Choi S, Gilman C, Bullock RM.

Quantitation of ischemic events after severe traumatic brain injury in humans: a simple scoring system.
J Neurosurg Anesthesiol. 2006 Jul;18(3):170-8.

Meyer EL, Waldenlind E, Marcus C.

beta-Receptor response to noradrenaline in cluster headache. A study of adipose tissue lipolysis.
Cephalalgia. 2006 Jul;26(7):831-6.

Morris KP, Forsyth RJ, Parslow RC, Tasker RC, Hawley CA; UK Paediatric Traumatic Brain Injury Study Group; Paediatric Intensive Care Society Study Group.

Intracranial pressure complicating severe traumatic brain injury in children: monitoring and management.
Intensive Care Med. 2006 Jul 28;

Audibert G, Charpentier C, Mertes PM.

[Cerebral microdialysis as a clinical tool.]
Ann Fr Anesth Reanim. 2006 May 16;

Ao X, Stenken JA.

Microdialysis sampling of cytokines.
Methods. 2006 Apr;38(4):331-41. Review.

Bhatia R, Hashemi P, Razzaq A, Parkin MC, Hopwood SE, Boutelle MG, Strong AJ.

Application of rapid-sampling, online microdialysis to the monitoring of brain metabolism during aneurysm surgery.
Neurosurgery. 2006 Apr;58(4 Suppl 2):

Hillered L, Persson L, Nilsson P, Ronne-Engstrom E, Enblad P.

Continuous monitoring of cerebral metabolism in traumatic brain injury: a focus on cerebral microdialysis.
Curr Opin Crit Care. 2006 Apr;12(2):112-8.

Vespa PM.

The implications of cerebral ischemia and metabolic dysfunction for treatment strategies in neurointensive care.
Curr Opin Crit Care. 2006 Apr;12(2):119-23.

Salci K, Nilsson P, Howells T, Ronne-Engstrom E, Piper I, Contant CF Jr, Enblad P.

Intracerebral Microdialysis and Intracranial Compliance Monitoring of Patients with Traumatic Brain Injury.
J Clin Monit Comput. 2006 Mar 10;

Vespa P, Boonyaputthikul R, McArthur DL, Miller C, Etchepare M, Bergsneider M, Glenn T, Martin N, Hovda D.

Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury.
Crit Care Med. 2006 Mar;34(3):850-6.

Boret H, Fesselet J, Meaudre E, Gaillard PE, Cantais E.

Cerebral microdialysis and P(ti)O2 for neuro-monitoring before decompressive craniectomy.
Acta Anaesthesiol Scand. 2006 Feb;50(2):252-4.

Caricato A, Pennisi M, Mancino A, Vigna G, Sandroni C, Arcangeli A, Antonelli M.

Levels of vancomycin in the cerebral interstitial fluid after severe head injury.
Intensive Care Med. 2006 Feb;32(2):325-8. Epub 2006 Jan 24.

Gorji A, Stemmer N, Rambeck B, Jurgens U, May T, Pannek HW, Behne F, Ebner A, Straub H, Speckmann EJ.

Neocortical microenvironment in patients with intractable epilepsy: potassium and chloride concentrations.
Epilepsia.
2006 Feb;47(2):297-310.

Lifschytz T, Segman R, Shalom G, Lerer B, Gur E, Golzer T, Newman ME.

Basic mechanisms of augmentation of antidepressant effects with thyroid hormone.
Curr Drug Targets. 2006 Feb;7(2):203-10.

Hillman J, Milos P, Yu ZQ, Sjogren F, Anderson C, Mellergard P.

Intracerebral microdialysis in neurosurgical intensive care patients utilising catheters with different molecular cut-off (20 and 100 kD).
Acta Neurochir (Wien). 2006 Jan 19;

Joukhadar C, Muller M.

Microdialysis : Current Applications in Clinical Pharmacokinetic Studies and its Potential Role in the Future.
Clin Pharmacokinet. 2005;44(9):895-913.

Vespa PM.

Multimodality monitoring and telemonitoring in neurocritical care: from microdialysis to robotic telepresence.
Curr Opin Crit Care. 2005 Apr;11(2):133-8.

Nordstrom CH.

The Lund concept: is this logical?
Acta Neurochir Suppl. 2005;95:475-80

Sarrafzadeh A, Haux D, Plotkin M, Ludemann L, Amthauer H, Unterberg A.

Bedside microdialysis reflects dysfunction of cerebral energy metabolism in patients with aneurysmal subarachnoid hemorrhage as confirmed by 15 O-H2 O-PET and 18 F-FDG-PET.
J Neuroradiol. 2005 Dec;32(5):348-51.

Clausen T, Khaldi A, Zauner A, Reinert M, Doppenberg E, Menzel M, Soukup J, Alves OL, Bullock MR.

Cerebral acid-base homeostasis after severe traumatic brain injury.
J Neurosurg. 2005 Oct;103(4):597-607.

Poca MA, Sahuquillo J, Mena MP, Vilalta A, Riveiro M.

[Recent advances in regional cerebral monitoring in the neurocritical patient: brain tissue oxygen pressure monitoring, cerebral microdialysis and near-infrared spectroscopy.]
Neurocirugia (Astur). 2005 Oct;16(5):385-410. Spanish

Hutchinson PJ, O’connell MT, Nortje J, Smith P, Al-Rawi PG, Gupta AK, Menon DK, Pickard JD.

Cerebral microdialysis methodology-evaluation of 20 kDa and 100 kDa catheters.
Physiol Meas. 2005 Aug;26(4):423-428. Epub 2005 Apr 11.

Noske DP, Peerdeman SM, Comans EF, Dirven CM, Knol DL, Girbes AR, Vandertop WP.

Cerebral microdialysis and positron emission tomography after surgery for aneurysmal subarachnoid hemorrhage in grade I patients.
Surg Neurol. 2005 Aug;64(2):109-15; discussion 115.

Sen J, Belli A, Petzold A, Russo S, Keir G, Thompson EJ, Smith M, Kitchen N.

Extracellular fluid S100B in the injured brain: a future surrogate marker of acute brain injury?
Acta Neurochir (Wien). 2005 Aug;147(8):897-900. Epub 2005 Apr 25.

Stocchetti N, Protti A, Lattuada M, Magnoni S, Longhi L, Ghisoni L, Egidi M, Zanier ER.

Impact of pyrexia on neurochemistry and cerebral oxygenation after acute brain injury.
J Neurol Neurosurg Psychiatry. 2005 Aug;76(8):1135-9.

Agren-Wilsson A, Eklund A, Koskinen LO, Bergenheim AT, Malm J.

Brain energy metabolism and intracranial pressure in idiopathic adult hydrocephalus syndrome.
J Neurol Neurosurg Psychiatry. 2005 Aug;76(8):1088-93.

Alves OL, Bullock R, Clausen T, Reinert M, Reeves TM.

Concurrent monitoring of cerebral electrophysiology and metabolism after traumatic brain injury: an experimental and clinical study.
J Neurotrauma. 2005 Jul;22(7):733-49

Hillman J, Aneman O, Anderson C, Sjogren F, Saberg C, Mellergard P.

A microdialysis technique for routine measurement of macromolecules in the injured human brain.
Neurosurgery. 2005 Jun;56(6):1264-8; discussion 1268-70.

Ronne Engstrom E, Hillered L, Enblad P, Karlsson T.

Cerebral interstitial levels of glutamate and glutamine after intravenous administration of nutritional amino acids in neurointensive care patients.
Neurosci Lett. 2005 May 11; [Epub ahead of print]

Wartenberg KE, Mayer SA.

Multimodal brain monitoring in the neurological intensive care unit: where does continuous EEG fit in?
J Clin Neurophysiol. 2005 Apr;22(2):124-7. Review.

Engstrom M, Polito A, Reinstrup P, Romner B, Ryding E, Ungerstedt U, Nordstrom CH.

Intracerebral microdialysis in severe brain trauma: the importance of catheter location.
J Neurosurg. 2005 Mar;102(3):460-9.

Springborg JB, Frederiksen HJ, Eskesen V, Olsen NV.

Trends in monitoring patients with aneurysmal subarachnoid haemorrhage.
Br J Anaesth. 2005 Mar;94(3):259-70. Epub 2004 Oct 29.

Berger C, Sakowitz OW, Kiening KL, Schwab S.

Neurochemical monitoring of glycerol therapy in patients with ischemic brain edema.
Stroke. 2005 Feb;36(2):e4-6. Epub 2004 Dec 23.

Bergenheim AT, Capala J, Roslin M, Henriksson R.

Distribution of BPA and metabolic assessment in glioblastoma patients during BNCT treatment: a microdialysis study.
J Neurooncol. 2005 Feb;71(3):287-93.

Stefani A, Fedele E, Galati S, Pepicelli O, Frasca S, Pierantozzi M, Peppe A, Brusa L, Orlacchio A, Hainsworth AH, Gattoni G, Stanzione P, Bernardi G, Raiteri M, Mazzone P.

Subthalamic stimulation activates internal pallidus: Evidence from cGMP microdialysis in PD patients.
Ann Neurol. 2005 Feb 24;57(3):448-452 [Epub ahead of print]

Hillered L, Vespa PM, Hovda DA.

Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis.
J Neurotrauma. 2005 Jan;22(1):3-41.

Battezzati A, Bertoli S.

Methods of measuring metabolism during surgery in humans: focus on the liver-brain relationship.
Curr Opin Clin Nutr Metab Care. 2004 Sep;7(5):523-30. Review.

Benjamin RK, Hochberg FH, Fox E, Bungay PM, Elmquist WF, Stewart CF, Gallo JM, Collins JM, Pelletier RP, de Groot JF, Hickner RC, Cavus I, Grossman SA, Colvin OM.

Review of microdialysis in brain tumors, from concept to application: first annual Carolyn Frye-Halloran symposium.
Neuro-oncol. 2004 Jan;6(1):65-74. Erratum in: Neuro-oncol. 2004 Apr;6(2):172.

Nordstrom CH.

Physiological and biochemical principles underlying volume-targeted therapy–the “Lund concept”.
Neurocrit Care. 2005;2(1):83-95. Review.

Ungerstedt U, Rostami E.

Microdialysis in neurointensive care.
Curr Pharm Des. 2004;10(18):2145-52. Review.

Consensus article 2004

Bellander BM, Cantais E, Enblad P, Hutchinson P, Nordstrom CH, Robertson C, Sahuquillo J, Smith M, Stocchetti N, Ungerstedt U, Unterberg A, Olsen NV.

Consensus meeting on microdialysis in neurointensive care.
Intensive Care Med. 2004 Dec;30(12):2166-9. Epub 2004 Nov 10.

Bellander BM, Cantais E, Enblad P, Hutchinson P, Nordstrom CH, Robertson C, Sahuquillo J, Smith M, Stocchetti N, Ungerstedt U, Unterberg A, Olsen NV.

Consensus meeting on microdialysis in neurointensive care.
Intensive Care Med. 2004 Dec;30(12):2166-9. Epub 2004 Nov 10.

 

Nelson DW, Bellander BM, Maccallum RM, Axelsson J, Alm M, Wallin M, Weitzberg E, Rudehill A.

Cerebral microdialysis of patients with severe traumatic brain injury exhibits highly individualistic patterns as visualized by cluster analysis with self-organizing maps.
Crit Care Med. 2004 Dec;32(12):2428-36.

Battezzati A, Bertoli S.

Methods of measuring metabolism during surgery in humans: focus on the liver-brain relationship.
Curr Opin Clin Nutr Metab Care. 2004 Sep;7(5):523-30. Review.

Tolias CM, Reinert M, Seiler R, Gilman C, Scharf A, Bullock MR.

Cerebral microdialysis of patients with severe traumatic brain injury exhibits highly individualistic patterns as visualized by cluster analysis with self-organizing maps.
Crit Care Med. 2004 Dec;32(12):2428-36.

Hlatky R, Valadka AB, Goodman JC, Contant CF, Robertson CS.

Patterns of energy substrates during ischemia measured in the brain by microdialysis.
J Neurotrauma. 2004 Jul;21(7):894-906.

Nordstrom CH.

The Lund concept: is this logical?
Acta Neurochir Suppl. 2005;95:475-80.

Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome.

Sarrafzadeh A, Haux D, Küchler I, Lanksch WR, Unterberg AW.
Journal of neurosurgery. 2004 Mar;100(3):400-6.

Bhardwaj A, Bosche B, Dohmen C, Graf R.

In vivo regional neurochemistry in stroke: clinical applications, limitations, and future directions * cerebral microdialysis in stroke patients: potentials and limitations of a method with longitudinal information: response.
Stroke. 2004 Apr;35(4):E74-6. Epub 2004 Mar 18

Coles JP.

Regional ischemia after head injury.
Curr Opin Crit Care. 2004 Apr;10(2):120-5. Review.

Ederoth P, Tunblad K, Bouw R, Lundberg CJ, Ungerstedt U, Nordstrom CH, Hammarlund-Udenaes M.

Blood-brain barrier transport of morphine in patients with severe brain trauma.
Br J Clin Pharmacol. 2004 Apr;57(4):427-35.

Longhi L, Stocchetti N.

Hyperoxia in head injury: therapeutic tool?
Curr Opin Crit Care. 2004 Apr;10(2):105-9. Review

Zald DH, Boileau I, El-Dearedy W, Gunn R, McGlone F, Dichter GS, Dagher A.

Dopamine transmission in the human striatum during monetary reward tasks.
J Neurosci. 2004 Apr 28;24(17):4105-12.

Johnston AJ, Steiner LA, Chatfield DA, Coles JP, Hutchinson PJ, Al-Rawi PG, Menon DK, Gupta AK.

Effect of cerebral perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury.
Intensive Care Med. 2004 Mar 27

Sarrafzadeh A, Haux D, Kuchler I, Lanksch WR, Unterberg AW.

Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome.
J Neurosurg. 2004 Mar;100(3):400-6

Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.

Skjøth-Rasmussen J, Schulz M, Kristensen SR, Bjerre P.
Journal of neurosurgery. 2004 Jan;100(1):8-15

Ungerstedt U, Rostami E.

Microdialysis in neurointensive care.
Curr Pharm Des. 2004;10(18):2145-52. Review.

Bourne JA.
Intracerebral microdialysis: 30 years as a tool for the neuroscientist.
Clin Exp Pharmacol Physiol. 2003 Jan-Feb;30(1-2):16-24. Review.

Janjua N, Mayer SA.

Cerebral vasospasm after subarachnoid hemorrhage.
Curr Opin Crit Care. 2003 Apr;9(2):113-9. Review.Dec 2003

Alessandri B, Heimann A, Filippi R, Kopacz L, Kempski O.

Moderate controlled cortical contusion in pigs: effects on multi-parametric neuromonitoring and clinical relevance.
J Neurotrauma. 2003 Dec;20(12):1293-305.

Meyer EL, Waldenlind E, Marcus C.

Diminished nocturnal lipolysis in cluster headache: A sign of central sympathetic dysregulation?
Neurology. 2003 Nov 11;61(9):1250-4

Sarrafzadeh AS, Kiening KL, Unterberg AW.

Neuromonitoring: brain oxygenation and microdialysis.
Curr Neurol Neurosci Rep. 2003 Nov;3(6):517-23. Review.

Bauer R, Gabl M, Obwegeser A, Galiano K, Barbach J, Mohsenipour I.

Neurochemical monitoring using intracerebral microdialysis during cardiac resuscitation.
Intensive Care Med. 2003 Oct 29

Stahl N, Schalen W, Ungerstedt U, Nordstrom CH.

Bedside biochemical monitoring of the penumbra zone surrounding an evacuated acute subdural haematoma.
Acta Neurol Scand. 2003 Sep;108(3):211-5.

Folkersma H, Peerdeman SM, Visser MC, Vriens EM, Girbes AR, Vandertop WP.

[Neuromonitoring of patients following severe brain trauma]
Ned Tijdschr Geneeskd. 2003 Jul 19;147(29):1394-8. Review. Dutch.

Richards DA, Tolias CM, Sgouros S, Bowery NG.

Extracellular glutamine to glutamate ratio may predict outcome in the injured brain: a clinical microdialysis study in children.
Pharmacol Res. 2003 Jul;48(1):101-9.

Magnoni S, Ghisoni L, Locatelli M, Caimi M, Colombo A, Valeriani V, Stoccehtti N.

Lack of improvement in cerebral metabolism after hyperoxia in severe head injury: a microdialysis study.
J Neurosurg. 2003 May;98(5):952-8.

Sarrafzadeh A, Haux D, Sakowitz O, Benndorf G, Herzog H, Kuechler I, Unterberg A.

Acute Focal Neurological Deficits in Aneurysmal Subarachnoid Hemorrhage. Relation of Clinical Course, CT Findings, and Metabolite Abnormalities Monitored With Bedside Microdialysis.
Stroke. 2003 May 15 [epub ahead of print]

Diaz-Parejo P, Stahl N, Xu W, Reinstrup P, Ungerstedt U, Nordstrom CH.

Cerebral energy metabolism during transient hyperglycemia in patients with severe brain trauma.
Intensive Care Med. 2003 Apr;29(4):544-50. Epub 2003 Mar 25.

Janjua N, Mayer SA.

Cerebral vasospasm after subarachnoid hemorrhage.
Curr Opin Crit Care. 2003 Apr;9(2):113-9. Review.

Nordstrom CH, Reinstrup P, Xu W, Gardenfors A, Ungerstedt U.

Assessment of the lower limit for cerebral perfusion pressure in severe head injuries by bedside monitoring of regional energy metabolism.
Anesthesiology. 2003 Apr;98(4):809-14.

Agren-Wilsson A, Roslin M, Eklund A, Koskinen LO, Bergenheim AT, Malm J.

Intracerebral microdialysis and CSF hydrodynamics in idiopathic adult hydrocephalus syndrome.
J Neurol Neurosurg Psychiatry. 2003 Feb;74(2):217-21

Hillered L, Persson L.

Microdialysis for neurochemical monitoring of the human brain.
Scand Cardiovasc J. 2003 Feb;37(1):13-7. No abstract available.

Mandybur GT, Miyagi Y, Yin W, Perkins E, Zhang JH.

Cytotoxicity of ventricular cerebrospinal fluid from Parkinson patients: correlation with clinical profiles and neurochemistry.
Neurol Res. 2003 Jan;25(1):104-11.

Roslin M, Henriksson R, Bergstrom P, Ungerstedt U, Bergenheim AT.

Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis.
J Neurooncol. 2003 Jan;61(2):151-60.

Marion DW, Puccio A, Wisniewski SR, Kochanek P, Dixon CE, Bullian L, Carlier P.

Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury.
Crit Care Med. 2002 Dec;30(12):2619-25

Cesarini KG, Enblad P, Ronne-Engstrom E, Marklund N, Salci K, Nilsson P, Hardemark HG, Hillered L, Persson L.

Early cerebral hyperglycolysis after subarachnoid haemorrhage correlates with favourable outcome.
Acta Neurochir (Wien). 2002 Nov;144(11):1121-31.

Winter CD, Iannotti F, Pringle AK, Trikkas C, Clough GF, Church MK.

A microdialysis method for the recovery of IL-1beta, IL-6 and nerve growth factor from human brain in vivo.
J Neurosci Methods. 2002 Sep 15;119(1):45-50.

Zamboni WC, Gervais AC, Egorin MJ, Schellens JH, Hamburger DR, Delauter BJ, Grim A, Zuhowski EG, Joseph E, Pluim D, Potter DM, Eiseman JL.

Inter- and intratumoral disposition of platinum in solid tumors after administration of cisplatin.
Clin Cancer Res. 2002 Sep;8(9):2992-9.

Tolias CM, Richards DA, Bowery NG, Sgouros S.

Extracellular glutamate in the brains of children with severe head injuries: a pilot microdialysis study.
Childs Nerv Syst. 2002 Aug;18(8):368-74.

Sarrafzadeh AS, Sakowitz OW, Kiening KL, Benndorf G, Lanksch WR, Unterberg AW.

Bedside microdialysis: a tool to monitor cerebral metabolism in subarachnoid hemorrhage patients?
Crit Care Med. 2002 May;30(5):1062-70.

Whalen MJ.

Predicting significant vasospasm in patients with subarachnoid hemorrhage: a role for bedside microdialysis?
Crit Care Med. 2002 May;30(5):1171-3. No abstract available

Hutchinson PJ, O’Connell MT, Kirkpatrick PJ, Pickard JD.

How can we measure substrate, metabolite and neurotransmitter concentrations in the human brain?
Physiol Meas. 2002 May;23(2):R75-109.

Johnston AJ, Gupta AK.

Advanced monitoring in the neurology intensive care unit: microdialysis.
Curr Opin Crit Care. 2002 Apr;8(2):121-7. Review.

Abi-Saab WM, Maggs DG, Jones T, Jacob R, Srihari V, Thompson J, Kerr D, Leone P, Krystal JH, Spencer DD, During MJ, Sherwin RS.

Striking Differences in Glucose and Lactate Levels Between Brain Extracellular Fluid and Plasma in Conscious Human Subjects: Effects of Hyperglycemia and Hypoglycemia.
J Cereb Blood Flow Metab. 2002 Mar;22(3):271-279.

Willis WD.

Role of neurotransmitters in sensitization of pain responses.
Ann N Y Acad Sci. 2001 Mar;933:142-56. Review.

Hlatky R, Furuya Y, Valadka AB, Goodman JC, Robertson CS.

Comparison of microdialysate arginine and glutamate levels in severely head-injured patient.
Acta Neurochir Suppl. 2002;81:347-9.

Hutchinson PJ, O’Connell MT, al-Rawi PG, Kett-White R, Gupta AK, Kirkpatrick PJ, Pickard JD.

Clinical cerebral microdialysis–determining the true extracellular concentration.
Acta Neurochir Suppl. 2002;81:359-62.

Kett-White R, Hutchinson PJ, Czosnyka M, Boniface S, Pickard JD, Kirkpatrick PJ.

Multi-modal monitoring of acute brain injury.
Adv Tech Stand Neurosurg. 2002;27:87-134.

Kett-White R, Hutchinson PJ, al-Rawi PG, Gupta AK, O’Connell MT, Pickard JD, Kirkpatrick PJ.

Extracellular lactate/pyruvate and glutamate changes in patients during per-operative episodes of cerebral ischaemia.
Acta Neurochir Suppl. 2002;81:363-5.

Kett-White R, Hutchinson PJ, Czosnyka M, al-Rawi P, Gupta A, Pickard JD, Kirkpatrick PJ.

Effects of variation in cerebral haemodynamics during aneurysm surgery on brain tissue oxygen and metabolism.
Acta Neurochir Suppl. 2002;81:327-9.

Sarrafzadeh AS, Sakowitz OW, Callsen TA, Lanksch WR, Unterberg AW.

Detection of secondary insults by brain tissue pO2 and bedside microdialysis in severe head injury.
Acta Neurochir Suppl. 2002;81:319-21.

Vespa P, Martin NA, Nenov V, Glenn T, Bergsneider M, Kelly D, Becker DP, Hovda DA.

Delayed increase in extracellular glycerol with post-traumatic electrographic epileptic activity: support for the theory that seizures induce secondary injury.
Acta Neurochir Suppl. 2002;81:355-7.

Meixensberger J, Kunze E, Barcsay E, Vaeth A, Roosen K.

Clinical cerebral microdialysis: brain metabolism and brain tissue oxygenation after acute brain injury.
Neurol Res. 2001 Dec;23(8):801-6.

Vissing J, MacLean DA, Vissing SF, Sander M, Saltin B, Haller RG.

The exercise metaboreflex is maintained in the absence of muscle acidosis: insights from muscle microdialysis in humans with McArdle’s disease.
J Physiol. 2001 Dec 1;537(Pt 2):641-9.

Pokela M, Biancari F, Rimpilainen J, Romsi P, Hirvonen J, Vainionpaa V, Kiviluoma K, Anttila V, Juvonen T.

The Role of Cerebral Microdialysis in Predicting the Outcome after Experimental Hypothermic Circulatory Arrest
Scand Cardiovasc J. 2001 Dec;35(6):395-402.

Schabitz WR, Berger C, Schellinger PD, Aschoff A, Steiner T, Schwab S.

Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction.
Cerebrovasc Dis. 2001;12(4):298-302.

Siddiqui MM, Shuaib A.

Intracerebral Microdialysis and Its Clinical Application: A Review
Methods 2001 Jan;23(1):83-94

Mendelowitsch A.

Neurosurgical University Clinic, Basel, Switzerland
Microdialysis: Intraoperative and Posttraumatic Applications in Neurosurgery.
Methods 2001 Jan;23(1):73-81
Key Words :  microdialysis; intraoperative monitoring; brain injury; glucose; lactate; glutamate; free radical scavengers.

Mertens P, Ghaemmaghami C, Bert L, Perret-Liaudet A, Guenot M, Naous H, Laganier L, Later R, Sindou M, Renaud B.

Microdialysis study of amino acid neurotransmitters in the spinal dorsal horn of patients undergoing microsurgical dorsal root entry zone lesioning. Technical note.
J Neurosurg. 2001 Jan;94(1 Suppl):165-73.

Bell MJ, Robertson CS, Kochanek PM, Goodman JC, Gopinath SP, Carcillo JA, Clark RS, Marion DW, Mi Z, Jackson EK.

Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury.
Crit Care Med. 2001 Feb;29(2):399-404.

Fedele E, Mazzone P, Stefani A, Bassi A, Ansaldo MA, Raiteri M, Altibrandi MG, Pierantozzi M, Giacomini P, Bernardi G, Stanzione P.

Microdialysis in Parkinsonian patient basal ganglia: acute apomorphine-induced clinical and electrophysiological effects not paralleled by changes in the release of neuroactive amino acids.
Exp Neurol. 2001 Feb;167(2):356-65.

Lindberger M, Tomson T, Wallstedt L, Stahle L.

Distribution of valproate to subdural cerebrospinal fluid, subcutaneous extracellular fluid, and plasma in humans: a microdialysis study.
Epilepsia. 2001 Feb;42(2):256-61.

Fried I, Wilson CL, Morrow JW, Cameron KA, Behnke ED, Ackerson LC, Maidment NT.

[1] Division of Neurosurgery, Box 957039, UCLA School of Medicine, 740 Westwood Plaza, Los Angeles, California 90095-7039, USA [2] Department of Psychiatry & Biobehavioral Sciences, Neuropsychatric Institute, UCLA School of Medicine, 760 Westwood Plaza, Los Angeles, California 90024.
Increased dopamine release in the human amygdala during performance of cognitive tasks
Nat Neurosci 2001 Feb;4(2):201-206

Ronne-Engstrom E, Cesarini KG, Enblad P, Hesselager G, Marklund N, Nilsson P, Salci K, Persson L, Hillered L.

Intracerebral microdialysis in neurointensive care: the use of urea as an endogenous reference compound.
J Neurosurg. 2001 Mar;94(3):397-402.

Bouw R, **Ederoth P, **Lundberg J, ***Ungerstedt U, ****Nordstrom CH, *Hammarlund-Udenaes M.

*Division of Biopharmaceutics and Pharmacokinetics, Uppsala University, **Department of Anesthesiology and Intensive Care, Lund University, ***Department of Physiology and Pharmacology, Karolinska Institute, ****Department of Clinical Neuroscience, Lund University, Sweden.
Increased blood-brain barrier permeability of morphine in a patient with severe brain lesions as determined by microdialysis
Acta Anaesthesiol Scand. 2001 Mar;45(3):390-392.

Galitzky J, Sengenes C, Thalamas C, Marques MA, Senard JM, Lafontan M, Berlan M.

The lipid-mobilizing effect of atrial natriuretic peptide is unrelated to sympathetic nervous system activation or obesity in young men.
J Lipid Res. 2001 Apr;42(4):536-44.

Konig K, Rickels E, Heissler HE, Zumkeller M, Samii M.

Artificial elevation of brain tissue glycerol by administration of a glycerol-containing agent. Case report.
J Neurosurg. 2001 Apr;94(4):621-3.
PMID: 11302662

Unterberg AW, Sakowitz OW, Sarrafzadeh AS, Benndorf G, Lanksch WR.

Role of bedside microdialysis in the diagnosis of cerebral vasospasm
following aneurysmal subarachnoid hemorrhage.
J Neurosurg. 2001 May;94(5):740-9.
Key Words: Cerebral vasospasm; Glutamate; Ischemia; Microdialysis; Nitric oxide; Subarachnoid hemorrhage

Feuerstein TH, Langemann H, Gratzl O, Mendelowitsch A.
A four lumen screwing device for multiparametric brain monitoring.
Acta Neurochir (Wien). 2000;142(8):909-12.
PMID: 11086830; UI: 20537665

Hutchinson PJ, al-Rawi PG, O’Connell MT, Gupta AK, Maskell LB, Hutchinson DB, Pickard JD, Kirkpatrick PJ.

Academic Department of Neurosurgery, University of Cambridge, UK.
Head injury monitoring using cerebral microdialysis and Paratrend multiparameter sensors.
Zentralbl Neurochir. 2000;61(2):88-94.

Marklund N, Ostman B, Nalmo L, Persson L, Hillered L.

Department of Neuroscience, Neurosurgery, Uppsala University, Sweden.
Hypoxanthine, uric acid and allantoin as indicators of in vivo free radical reactions. Description of a HPLC method and human brain microdialysis data.
Acta Neurochir (Wien). 2000;142(10):1135-41; discussion 1141-2.

Hutchinson PJ, Al-Rawi PG, O’Connell MT, Gupta AK, Pickard JD, Kirkpatrick PJ.
Biochemical changes related to hypoxia during cerebral aneurysm surgery: combined microdialysis and tissue oxygen monitoring: case report.
Neurosurgery. 2000 Jan;46(1):201-5; disc

Hutchinson PJ , Hutchinson DB , Barr RH , Burgess F , Kirkpatrick PJ , Pickard JD

A new cranial access device for cerebral monitoring.
Br J Neurosurg 2000 Feb 14:1 46-8

Peerdeman SM, Girbes AR, Vandertop WP
Cerebral microdialysis as a new tool for neurometabolic monitoring.
Intensive Care Med. 2000 Jun;26(6):662-9
PMID: 10945381; UI: 20399478

Hutchinson PJ, O’Connell MT, Al-Rawi PG, Maskell LB, Kett-White R, Gupta AK, Richards HK, Hutchinson DB, Kirkpatrick PJ, Pickard JD.

Academic Department of Neurosurgery and Wolfson Brain Imaging Centre, University of Cambridge, United Kingdom. Peter.Hutchinson@dial.pipex.com
Clinical cerebral microdialysis: a methodological study.
J Neurosurg. 2000 Jul;93(1):37-43.

Grande PO, Moller AD, Nordstrom CH, Ungerstedt U.

Low-dose prostacyclin in treatment of severe brain trauma evaluated with microdialysis and jugular bulb oxygen measurements.
Acta Anaesthesiol Scand. 2000 Aug;44(7):886-94.

Reinstrup P, Stahl N, Mellergard P, Uski T, Ungerstedt U, Nordstrom CH.

Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery.
Neurosurgery. 2000 Sep;47(3):701-9; discussion 709-10.

Yamaguchi S, Nakahara K, Miyagi T, Tokutomi T, Shigemori M.
Neurochemical monitoring in the management of severe head-injured patients with hypothermia.
Neurol Res. 2000 Oct;22(7):657-64.
PMID: 11091969; UI: 20543462

Reinert M, Khaldi A, Zauner A, Doppenberg E, Choi S, Bullock R.

High level of extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure.

Neurosurg. 2000 Nov;93(5):800-7

Staub F, Graf R, Gabel P, Kochling M, Klug N, Heiss WD.
Multiple interstitial substances measured by microdialysis in patients with subarachnoid hemorrhage.
Neurosurgery. 2000 Nov;47(5):1106-15; discussion 1115-6.
PMID: 11063103; UI: 20515108

Schulz MK, Wang LP, Tange M, Bjerre P.
Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage.
J Neurosurg. 2000 Nov;93(5):808-14.
PMID: 11059662; UI: 20511441

Alessandri B, Doppenberg E, Bullock R, Woodward J, Choi S, Koura S, Young HF

Department of Neurosurgery, Virginia Commonwealth University, Medical College of Virginia, Richmond, USA
Glucose and lactate metabolism after severe human head injury: influence of excitatory neurotransmitters and injury type.
Acta Neurochir Suppl (Wien). 1999;75:21-4.

Alessandri B, Doppenberg E, Zauner A, Woodward J, Choi S, Bullock R
Evidence for time-dependent glutamate-mediated glycolysis in head-injured patients: a microdialysis study.
Acta Neurochir Suppl (Wien). 1999;75:25-8.

Doppenberg EM, Reinert M, Zauner A, Massie TS, Bullock R.
Determinants of cerebral extracellular potassium after severe human head injury.
Acta Neurochir Suppl (Wien). 1999;75:31-4.

Goodman JC, Valadka AB, Gopinath SP, Uzura M, Grossman RG, Robertson CS.
Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA.
Simultaneous measurement of cortical potassium, calcium, and magnesium levels measured in head injured patients using microdialysis with ion chromatography.
Acta Neurochir Suppl (Wien). 1999;75:35-7.

Hillered L, Persson L.

Neurochemical monitoring of the acutely injured human brain
Scand J Clin Invest Suppl 1999; 229:9-18

Hillered L, Persson L.

Theory and practice of microdialysis–prospect for future clinical use.

Acta Neurochir Suppl (Wien). 1999;75:3-6.

Hutchinson PJ, O’Connell MT, Maskell LB, Pickard JD.
University Department of Neurosurgery, Addenbrooke’s Hospital, Cambridge, UK.
Monitoring by subcutaneous microdialysis in neurosurgical intensive care.
Acta Neurochir Suppl (Wien). 1999;75:57-9.

Kawamata T, Katayama Y, Satoh M, Mori T, Maeda T.
Department of Neurological Surgery, Nihon University, School of Medicine, Tokyo, Japan
Intraoperative enzyme-amperometric monitoring of extracellular glutamate concentration with a dialysis electrode in ischemic human brain.
Acta Neurochir Suppl (Wien). 1999;75:11-4

Letarte PB, Puccio AM, Brown SD, Marion DW.
Effect of hypocapnea on CBF and extracellular intermediates of secondary brain injury.
Acta Neurochir Suppl (Wien). 1999;75:45-7.

Persson L, Enblad P.

Neurointensive care of aneurysmal SAH.
Acta Neurochir Suppl (Wien). 1999;72:73-80. Review.

Yamamoto T, Rossi S, Stiefel M, Doppenberg E, Zauner A, Bullock R, Marmarou A.

Division of Neurosurgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA
CSF and ECF glutamate concentrations in head injured patients.
Acta Neurochir Suppl (Wien). 1999;75:17-9..

Connelly CA
Microdialysis update: optimizing the advantages
J Physiol (Lond) 1999 Jan 15;514 (Pt2):303

Berger C, Annecke A, Aschoff A, Spranger M, Schwab S
Neurochemical monitoring of fatal middle cerebral artery infarction.
Stroke 1999 Feb 30:2 460-3

Hans P, Damas F.
[ Evaluation of cerebral metabolism].
Ann Fr Anesth Reanim. 1999 May;18(5):599-603. Review. French.

Hutchinson PJ, Al-Rawi PG, O’Connell MT, Gupta AK, Maskell LB, Hutchinson DB, Pickard JD, Kirkpatrick PJ.

Monitoring of brain metabolism during aneurysm surgery using microdialysis and brain multiparameter sensors.

Neurol Res. 1999 Jun;21(4):352-8.

Goodman JC, Valadka AB, Gopinath SP, Uzura M, Robertson CS.
Extracellular lactate and glucose alterations in the brain after head injury measured by microdialysis.
Crit Care Med. 1999 Sep;27(9):1965-73.

Marion DW.
Lactate and traumatic brain injury.
Crit Care Med. 1999 Sep;27(9):2063-4. No abstract available.

Dizdar N, Granerus AK, Hannestad U, Kullman A, Ljungdahl A, Olsson JE, Kagedal B.

L-dopa pharmacokinetics studied with microdialysis in patients with Parkinson’s disease and a history of malignant melanoma.
Acta Neurol Scand. 1999 Oct;100(4):231-7.

Dizdar N, Kullman A, Norlander B, Olsson JE, Kagedal B.

Human pharmacokinetics of L-3,4-dihydroxyphenylalanine studied with microdialysis.
Clin Chem. 1999 Oct;45(10):1813-20.

E, Fields TA, MacDonald KA, Morrow JW, Ackerson L.
Cerebral microdialysis combined with single-neuron and electroencephalographic recording in neurosurgical patients. Technical note.
J Neurosurg. 1999 Oct;91(4):697-705.

Menzel M, Doppenberg EM, Zauner A, Soukup J, Reinert MM, Clausen T, Brockenbrough PB, Bullock R.
Cerebral oxygenation in patients after severe head injury: monitoring and effects of arterial hyperoxia on cerebral blood flow, metabolism and intracranial pressure.
J Neurosurg Anesthesiol. 1999 Oct;11(4):240-51.

Nilsson OG, Brandt L, Ungerstedt U, Saveland H.
Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration.
Neurosurgery. 1999 Nov;45(5):1176-84; discussion 1184-5.

Rada P, Tucci S, Teneud L, Paez X, Perez J, Alba G, Garcia Y, Sacchettoni S, del Corral J, Hernandez L.
Monitoring gamma-aminobutyric acid in human brain and plasma microdialysates using micellar electrokinetic chromatography and laser-induced fluorescence detection.
J Chromatogr B Biomed Sci Appl. 1999 Nov 26;735(1):1-10.

Radegran G.

Limb and skeletal muscle blood flow measurements at rest and during exercise in human subjects.
Proc Nutr Soc. 1999 Nov;58(4):887-98.

Alessandri B, Doppenberg E, Zauner A, Woodward J, Young HF, Bullock R
Cortical extracellular sodium transients after human head injury: an indicator of secondary brain damage?
Acta Neurochir Suppl (Wien) 1998 71: 237-40

Baunach S, Meixensberger J, Gerlach M, Lan J, Roosen K
Intraoperative microdialysis and tissue-pO2 measurement in human glioma.
Acta Neurochir Suppl (Wien) 1998 71: 241-3

Koura SS, Doppenberg EM, Marmarou A, Choi S, Young HF, Bullock R
Relationship between excitatory amino acid release and outcome after severe human head injury.
Acta Neurochir Suppl (Wien) 1998 71: 244-6

Mendelowitsch A, Sekhar LN, Wright DC, Nadel A, Miyashita H, Richardson R, Kent M, Shuaib A
An increase in extracellular glutamate is a sensitive method of detecting ischaemic neuronal damage during cranial base and cerebrovascular surgery. An in vivo microdialysis study.
Acta Neurochir (Wien) 1998 140:4 349-55;

Robertson CS, Gopinath SP, Uzura M, Valadka AB, Goodman JC
Metabolic changes in the brain during transient ischemia measured with microdialysis.
Neurol Res 1998 20 Suppl 1: S91-4

Sarrafzadeh AS, Unterberg AW, Lanksch WR.
Bedside-microdialysis for early detection of vasospasm after subarachnoid hemorrhage. Case report and review of the literature.
Zentralbl Neurochir. 1998;59(4):269-73.

Mochizuki T, Yamatodani A
[Release of biogenic amines in the brain during sleep-wakefulness cycle]
Nippon Rinsho 1998 Feb 56:2 290-5

Mendelowitsch A, Sekhar LN, Caputy AJ, Shuaib A
Intraoperative on-line monitoring of cerebral pH by microdialysis in neurosurgical procedures.
Neurol Res 1998 Mar 20:2 142-8

Hillered L, Valtysson J, Enblad P, Persson L
Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain.
J Neurol Neurosurg Psychiatry 1998 Apr 64:4 486-91

Bolo N, Nédélec JF, Muzet M, De Witte P, Dahchour A, Durbin P, Macher JP
Central effects of acamprosate: part 2. Acamprosate modifies the brain in-vivo proton magnetic resonance spectrum in healthy young male volunteers
Psychiatry Res 1998 May 20 82:2 115-27

Mendelowitsch A, Mergner GW, Shuaib A, Sekhar LN
Cortical brain microdialysis and temperature monitoring during hypothermic circulatory arrest in humans.
J Neurol Neurosurg Psychiatry 1998 May 64:5 611-8

Valadka AB, Goodman JC, Gopinath SP, Uzura M, Robertson CS.

Comparison of brain tissue oxygen tension to microdialysis-based measures of
cerebral ischemia in fatally head-injured
J Neurotrauma. 1998 Jul;15(7):509-19.

Bullock R, Zauner A, Woodward JJ, Myseros J, Choi SC, Ward JD, Marmarou A, Young HF
Factors affecting excitatory amino acid release following severe human head injury.
J Neurosurg 1998 Oct 89:4 507-18

Endres CJ, Carson RE
Assessment of dynamic neurotransmitter changes with bolus or infusion delivery of neuroreceptor ligands.
J Cereb Blood Flow Metab 1998 Nov 18:11 1196-210

Vespa P, Prins M, Ronne-Engstrom E, Caron M, Shalmon E, Hovda DA, Martin NA, Becker DPIncrease in extracellular glutamate caused by reduced cerebral perfusion pressure and seizures after human traumatic brain injury: a microdialysis study.
J Neurosurg 1998 Dec 89:6 971-82

Matz PG, Pitts L.

Monitoring in traumatic brain injury.
Clin Neurosurg. 1997;44:267-94. Review

Ungerstedt U, Bäckström T, Hallström Å, Grände PO, Mellergård P, Nordström CH:
Microdialysis in normal and injured human brain. In: Physiology, Stress,and Malnutrition: Functional Correlates, Nutritional Intervention ( Eds.Kinney JM, Tucker HN). Lippincott-Raven Publishers,Philadelphia, New-York, 1997 pp.361-374.

Hamani C, Luer MS, Dujovny M
Reprint Available From: Dujovny M Univ Illinois Dept Neurosurg Inst Neuropsychiat Coll Med Mc 799 912 S Wood St Chicago, Il 60612 Usa Univ Illinois Dept Neurosurg Inst Neuropsychiat Coll Med Chicago, Il 60612 Usa Univ Arkansas Med Sci Coll Pharm Dept Pharm Practice Little Rock, Ar Usa
Microdialysis in the human brain – review of its applications.
Neurol Res 1997 Jun;19(3):281-8.

Himmelheber AM, Sarter M, Bruno JP
Reprint Available From: Bruno Jp Ohio State Univ Dept Psychol 31 Townshend Hall Columbus, Oh 43210 Usa Ohio State Univ Dept Psychol Columbus, Oh 43210 Usa Ohio State Univ Program Neurosci Columbus, Oh 43210 Usa
Operant performance and cortical acetylcholine release – role of response rate, reward density, and non-contingent stimuli.
Cognitive Brain Research 1997 Jul;6(1):23-36.

Zauner A, Doppenberg EMR, Woodward JJ, Choi SC, Young HF, Bullock R
Reprint Available From: Zauner A Virginia Commonwealth Univ Med Coll Virginia Div Neurosurg Pob 980631 Richmond, Va 23298 Usa Virginia Commonwealth Univ Med Coll Virginia Dept Pharmacol Richmond, Va 23298 Usa Virginia Commonwealth Univ Med Coll Virginia Dept Biostat Richmond, Va 23298 Usa
Continuous monitoring of cerebral substrate delivery and clearance – initial experience in 24 patients with severe acute brain injuries.
Neurosurgery 1997 Nov;41(5):1082-91.

Karlsson AK, Elam M, Friberg P, Sullivan L, Attvall S, Lonnroth P
Reprint Available From: Karlsson Ak Sahlgrens Univ Hosp Inst Clin Neurosci Lundberg Lab Diabet Res Spinal Unit S-41345 Gothenburg Sweden Sahlgrens Univ Hosp Dept Neurol Lundberg Lab Diabet Res S-41345 Gothenburg Sweden Sahlgrens Univ Hosp Dept Clin Neurosci Lundberg Lab Diabet Res S-41345 Gothenburg Sweden Sahlgrens Univ Hosp Inst Internal Med Lundberg Lab Diabet Res S-41345 Gothenburg Sweden
Peripheral afferent stimulation of decentralized sympathetic neurons activates lipolysis in spinal cord-injured subjects.
Metabolism: Clinical & Experimental 1997 Dec;46(12):1465-9.

Stover JF, Pleines UE, Morgantikossmann MC, Kossmann T, Lowitzsch K, Kempski OS
Reprint Available From: Stover Jf Univ Zurich Hosp Dept Trauma Surg Ramistr 100 Ch-8091 Zurich Switzerland Inst Neurosurg Pathophysiol Mainz Germany Klinikum Stadt Ludwigshafen Dept Neurol D-6700 Ludwigshafen Germany
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
Eur J Clin Invest 1997 Dec;27(12):1038-43.1996Czosnyka M, Kirkpatrick PJ, Pickard JD
Wolfson Brain Imaging Centre, University of Cambridge, England.
Multimodal monitoring and assessment of cerebral haemodynamic reserve after severe head injury.
Cerebrovasc-Brain-Metab-Rev 1996 Winter;8(4):273-95.

Goodman JC, Gopinath SP, Valadka AB, Narayan RK, Grossman RG,
Simpson RK Jr, Robertson CS
Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Lactic acid and amino acid fluctuations measured using microdialysis reflect
physiological derangements in head injury.
Acta-Neurochir-Suppl-Wien 1996;67:37-9.

Landolt H.; H. Langemann and B. Alessandri,
A Concept for the Introduction of Cerebral Microdialysis in Neurointensive Care
1996, Acta Neurochir Suppl Wien, 67: 31-6

Langemann H.; J. Habicht, A. Mendelowitsch, A. Kanner, B. Alessandri, H. Landolt and O. Gratzl
Microdialytic Monitoring During a Cardiovascular Operation,
1996, Acta Neurochir Suppl Wien, 67: 70-4

Lieberman D.
Letter to the Editor: Intracerebral Microdialysis,

Lorentzen H.; F. Kallehave, H. J. Kolmos, U. Knigge, J. Bulow and F. Gottrup
Gentamicin Concentrations in Human Subcutaneous Tissue , 1996, Antimicrob Agents Chemother, 1785-9

Mendelowitsch A, Langemann H, Alessandri B, Kanner A, Landolt H, Gratzl O
Department of Research, Cantonal Hospital, Basel, Switzerland.
Microdialytic monitoring of the cortex during neurovascular surgery.
Acta-Neurochir-Suppl-Wien 1996;67:48-52.

Nilsson OG, Saveland H, Boris Moller F, Brandt L, Wieloch T
Department of Neurosurgery, Lund University Hospital, Sweden.
Increased levels of glutamate in patients with subarachnoid haemorrhage as measured by intracerebral microdialysis.
Acta-Neurochir-Suppl-Wien 1996;67:45-7.

Patsalos PN, O’Connell MT, Doheny HC, Sander JW, Shorvon SD
National Society for Epilepsy, Chalfont Centre for Epilepsy, Chalfont St Peter, Bucks, UK.
Antiepileptic drug pharmacokinetics in patients with epilepsy using a new microdialysis probe: preliminary observations.
Acta-Neurochir-Suppl-Wien 1996;67:59-62.
1996, J Neurosurg, 85: 984-5

Zauner A, Bullock R, Kuta AJ, Woodward J, Young HF
Division of Neurosurgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA.
Glutamate release and cerebral blood flow after severe human head injury.
Acta-Neurochir-Suppl-Wien 1996;67:40-4.

Saveland H, Nilsson OG, Boris Moller F, Wieloch T, Brandt L
Department of Neurosurgery, Lund University Hospital, Sweden.
Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage.
Neurosurgery 1996 Jan;38(1):12-9; discussion 19-20.

Persson L, Valtysson J, Enblad P, Warme PE, Cesarini K, Lewen A, Hillered L
Department of Neurosurgery, Uppsala University Hospital, Sweden.
Neurochemical monitoring using intracerebral microdialysis in patients with subarachnoid hemorrhage.
J-Neurosurg 1996 Apr;84(4):606-16.

Kanthan R, Shuaib A, Griebel R, el Alazounni H, Miyashita H, Kalra J
Department of Medicine (Neurology), Royal University Hospital Saskatoon, SK.
Evaluation of monoaminergic neurotransmitters in the acute focal ischemic human brain model by intracerebral in vivo microdialysis.
Neurochem-Res 1996 May;21(5):563-6.

Kanthan R, Shuaib A, Griebel R, Miyashita H, Kalra J
Department of Medicine (Neurology), Saskatchewan Stroke Research Centre, College of Medicine, Saskatoon, Canada.
Glucose-induced decrease in glutamate levels in ischemic human brain by in-vivo microdialysis.
Neurosci-Lett 1996 May 17;209(3):207-9.

Whittle IR, Piper IR.
Clinical evaluation of extracellular amino acids in severe head trauma by intracerebral in vivo microdialysis [letter; comment].
J-Neurol-Neurosurg-Psychiatry 1996 Jun;60(6):703.

Enblad P, Valtysson J, Andersson J, Lilja A, Valind S, Antoni G, Langstrom B,
Hillered L, Persson L
Department of Neurosurgery, Uppsala University Hospital, Sweden.
Simultaneous intracerebral microdialysis and positron emission tomography in the detection of ischemia in patients with subarachnoid hemorrhage.
J-Cereb-Blood-Flow-Metab 1996 Jul;16(4):637-44.

Bachli H, Langemann H, Mendelowitsch A, Alessandri B, Landolt H, Gratzl O
Reprint Available From: Bachli H Univ Basel Kantonsspital Neurochirurg Klin Ch-4031 Basel Switzerland Univ Basel Kantonsspital Res Dept Ch-4031 Basel Switzerland Kantonsspital Neurosurg Clin Ch-5000 Aarau Switzerland
Microdialytic monitoring during cerebrovascular surgery.
Neurol Res 1996 Aug;18(4):370-6.

Goodman JC, Valadka AB, Gopinath SP, Cormio M, Robertson CS
Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA.
Lactate and excitatory amino acids measured by microdialysis are decreased
by pentobarbital coma in head-injured patients.
J-Neurotrauma 1996 Oct;13(10):549-56.

O’Connell MT, Tison F, Quinn NP, Patsalos PN
Pharmacology and Therapeutics Unit, National Hospital for Neurology and Neurosurgery, London, UK.
Clinical drug monitoring by microdialysis: application to levodopa therapy in Parkinson’s disease.
Br-J-Clin-Pharmacol 1996 Dec;42(6):765-9.

Rossi J 3rd, Ritchie GD, Macys DA, Still KR
Naval Medical Research Institute Detachment (Toxicology), Wright-Patterson AFB, Ohio 45433-7903, USA.
An overview of the development, validation, and application of neurobehavioral and neuromolecular toxicity assessment batteries: potential applications to combustion toxicology.
Toxicology 1996 Dec 31;115(1-3):107-17.

Shuaib A, Kanthan R, Goplen G, Griebel R, el Azzouni H, Miyashita H, Liu L, Hogan T
Department of Medicine (Neurology), Royal University Hospital, Saskatoon, SK, Canada.
In-vivo microdialysis study of extracellular glutamate response to temperature variance in subarachnoid hemorrhage.
Acta-Neurochir-Suppl-Wien 1996;67:53-8.

Stahle L, Alm C, Ekquist B, Lundquist B, Tomson T
Department of Clinical Pharmacology, Karolinska Institute, Huddinge Hospital, Stockholm, Sweden.
Monitoring free extracellular valproic acid by microdialysis in epileptic patients.
Ther-Drug-Monit 1996 Feb;18(1):14-8.

Wilson CL, Maidment NT, Shomer MH, Behnke EJ, Ackerson L, Fried I, Engel J
Reprint Available From: Wilson Cl Univ Calif Los Angeles Sch Med Dept Neurol Los Angeles, Ca 90024 Usa Univ Calif Los Angeles Sch Med Dept Psychiat & Biobehav Sci Los Angeles, Ca 90024 Usa Univ Calif Los Angeles Sch Med Dept Neurobiol Los Angeles, Ca 90024 Usa Univ Calif Los Angeles Sch Med Div Neurol Surg Los Angeles, Ca 90024 Usa Univ Calif Los Angeles Sch Med Brain Res Inst Los Angeles, Ca 90024 Usa
Comparison of seizure related amino acid release in human epileptic hippocampus versus a chronic, kainate rat model of hippocampal epilepsy.
Epilepsy Res 1996 Dec;26(1):245-54.1995Hovda D. A.; S. M. Lee, M. L. Smith, S. V. Stuck, M. Bergsneider, D. Kelly, E. Shalmon, N. Martin, M. Caron, J. Mazziotta, M. Phelps and D. P. Becker
The Neurochemical and Metabolic Cascade Following Brain Injury: Moving from Animal Models to Man,
1995, J Neurotrauma, 12: 903-6

Redgate ES, Boggs S, Grudziak A, Deutsch M
Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, USA.
Polyamines in brain tumor therapy.
J-Neurooncol 1995;25(2):167-79.

Karlsson AK, Attvall S, Jansson PA, Sullivan L, Lonnroth P
Department of Neurosurgery, University of Gothenburg, Sahlgrenska Hospital, Sweden.
Influence of the sympathetic nervous system on insulin sensitivity and adipose tissue metabolism: a study in spinal cord-injured subjects.
Metabolism 1995 Jan;44(1):52-8.

Hamberger A, Runnerstam M, Nystrom B, Starmark JE, von Essen C
Department of Anatomy and Cell Biology, University of Goteborg, Sweden.
The neuronal environment after subarachnoid haemorrhage–correlation of amino acid and nucleoside levels with post-operative recovery.
Neurol-Res 1995 Apr;17(2):97-105.

Kanthan R, Shuaib A, Griebel R, Miyashita H
Department of Medicine (Neurology), Royal University Hospital, Saskatoon, Saskatchewan, Canada.
Intracerebral human microdialysis. In vivo study of an acute focal ischemic model of the human brain.
Stroke 1995 May;26(5):870-3.

Kanthan R, Shuaib A, Goplen G, Miyashita H
Saskatchewan Stroke Research Centre, Department of Medicine (Neurology), College of Medicine, University of Saskatchewan, Saskatoon, Canada.
A new method of in-vivo microdialysis of the human brain.
J-Neurosci-Methods 1995 Aug;60(1-2):151-5.

Bullock R, Zauner A, Myseros JS, Marmarou A, Woodward JJ, Young HF
Division of Neurosurgery, School of Medicine, Medical College of Virginia, Richmond 23298-0631, USA.
Evidence for prolonged release of excitatory amino acids in severe human head trauma. Relationship to clinical events.
Ann-N-Y-Acad-Sci 1995 Sep 15;765:290-7; discussion 298.

Hillered L, Persson L
Department of Clinical Chemistry, Uppsala University Hospital, Sweden.
Parabanic acid for monitoring of oxygen radical activity in the injured human brain.
Neuroreport 1995 Sep 11;6(13):1816-20.

Kanthan R, Shuaib A
Saskatchewan Stroke Research Centre, University of Saskatchewan, Saskatoon, Canada.
Clinical evaluation of extracellular amino acids in severe head trauma by intracerebral in vivo microdialysis [see comments].
J-Neurol-Neurosurg-Psychiatry 1995 Sep;59(3):326-7.

Bullock R, Zauner A, Woodward J, Young HF
Division of Neurosurgery, Medical College of Virginia, Richmond 23298, USA.
Massive persistent release of excitatory amino acids following human occlusive stroke.
Stroke 1995 Nov;26(11):2187-9.

Kanthan R, Goplen G, Griebel R, Miyashita H, Burbridge B, Kalra I, Shuaib A.
Clinical evaluation of vasospasm in subarachnoid haemorrhage by in vivo microdialysis [letter].
J-Neurol-Neurosurg-Psychiatry 1995 Dec;59(6):646-7.

Robertson CS, Gopinath SP, Goodman JC, Contant CF, Valadka AB, Narayan RK
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77030, USA.
SjvO2 monitoring in head-injured patients.
J-Neurotrauma 1995 Oct;12(5):891-6.

Landolt H.; H. Langemann, A. Mendelowitsch, O. Gratzl
Neurochemical Monitoring and On-Line pH Measurements Using Brain Microdialysis in Patients in Intensive Care,
1994, Acta Neurochir Suppl Wien, 60: 475-8

During MJ, Fried I, Leone P, Katz A, Spencer DD
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510.
Direct measurement of extracellular lactate in the human hippocampus during spontaneous seizures.
J-Neurochem 1994 Jun;62(6):2356-61

Scheyer RD, During MJ, Hochholzer JM, Spencer DD, Cramer JA, Mattson RH
Department of Neurology, Yale University School of Medicine, New Haven, CT.
Phenytoin concentrations in the human brain: an in vivo microdialysis study.
Epilepsy-Res 1994 Jul;18(3):227-32.

Scheyer RD, During MJ, Spencer DD, Cramer JA, Mattson RH
Department of Neurology, Yale University School of Medicine, New Haven, CT.
Measurement of carbamazepine and carbamazepine epoxide in the human brain using in vivo microdialysis.
Neurology 1994 Aug;44(8):1469-72.

Meldrum BS
Department of Neurology, Institute of Psychiatry, London, United Kingdom.
The role of glutamate in epilepsy and other CNS disorders.
Neurology 1994 Nov;44(11 Suppl 8):S14-23.1993Sybirska E, Seibyl J P, Bremner J D, Baldwin R M, Al-Tikriti M. S., Bradberry C, Malison R T, Zea-Ponce Y, Zoghbi S.
[123I]iomazenil SPECT Imaging Demonstrates Significant Benzodiazepine Receptor Reserve in Human and Nonhuman Primate Brain
1993, Neuropharmacology, 32: 671-80

Mindermann T, Landolt H, Langemann H, Gratzl O
Departement Forschung, Kantonsspital Basel.
[Cerebral microdialysis in neurological and neurosurgical research and clinical application in neurology and neurosurgery].
Schweiz-Rundsch-Med-Prax 1993 Jan 5;82(1):9-11.

During MJ, Spencer DD
Department of Surgery, Yale University School of Medicine, New Haven, CT 06510.
Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain [see comments].
Lancet 1993 Jun 26;341(8861):1607-10.

During MJ, Spencer DD
Department of Surgery, Yale University School of Medicine, New Haven, CT 06510.
Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain [see comments].
Lancet 1993 Jun 26;341(8861):1607-10.

Meldrum BS
Department of Neurology, Institute of Psychiatry, London, UK.
Intracerebral microdialysis and seizure initiation [comment].
Lancet 1993 Jun 26;341(8861):1627.

Chazov EI.
[New approaches to the study of central nervous system regulation mechanisms].
Vestn-Ross-Akad-Med-Nauk 1993 Jul-1993 Aug 31;(7):31-4.

1992Hillered L, Persson L, Carlson H, Ungerstedt U, Ronne Engstrom E, Nilsson P
Uppsala University Hospital, Sweden.
Studies on excitatory amino acid receptor-linked brain disorders in rat and man using in vivo microdialysis.
Clin-Neuropharmacol 1992;15 Suppl 1 Pt A:695A-6A.

Ronquist G, Hugosson R, Sjolander U, Ungerstedt U
Department of Clinical Chemistry, University Hospital, University of Uppsala, Sweden.
Treatment of malignant glioma by a new therapeutic principle.
Acta-Neurochir-Wien 1992;114(1-2):8-11.

Persson L, Hillered L
Department of Neurosurgery, University Hospital, Uppsala, Sweden.
Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis.
J-Neurosurg 1992 Jan;76(1):72-80.

Flentge F, Venema K, Koch T, Korf J
Department of Biological Psychiatry, University of Groningen, The Netherlands.
An enzyme-reactor for electrochemical monitoring of choline and acetylcholine: applications in high-performance liquid chromatography, brain tissue, microdialysis and cerebrospinal fluid.
Anal-Biochem 1992 Aug 1;204(2):305-10.

Ronne Engstrom E, Hillered L, Flink R, Spannare B, Ungerstedt U, Carlson H
Department of Neurosurgery, University Hospital of Uppsala, Sweden.
Intracerebral microdialysis of extracellular amino acids in the human epileptic focus.
J-Cereb-Blood-Flow-Metab 1992 Sep;12(5):873-6.1991

 

Ungerstedt U
Department of Pharmacology, Karolinska Institute, Stockholm, Sweden.
Microdialysis–principles and applications for studies in animals and man.
J-Intern-Med 1991 Oct;230(4):365-73.

1990Whittle IR.
Intracerebral microdialysis: a new method in applied clinical neuroscience research [editorial].
Br-J-Neurosurg 1990;4(6):459-62.

 

Pickar D
Clinical Neuroscience Branch, National Institute of Mental Health, Bethesda, Maryland.
A clinical perspective on microdialysis.
Prog-Neuropsychopharmacol-Biol-Psychiatry 1990;14 Suppl:S59-62.

Meyerson BA, Linderoth B, Karlsson H, Ungerstedt U
Dept of Neurosurgery, Karolinska Hospital, Stockholm, Sweden.
Microdialysis in the human brain: extracellular measurements in the thalamus of parkinsonian patients.
Life-Sci 1990;46(4):301-8.

Korf J, de Boer J
Department of Biological Psychiatry, Groningen, The Netherlands.
Lactography as an approach to monitor glucose metabolism on-line in brain and muscle.
Int-J-Biochem 1990;22(12):1371-8.

Hillered L, Persson L, Ponten U, Ungerstedt U
Department of Neurosurgery, University Hospital, Uppsala, Sweden.
Neurometabolic monitoring of the ischaemic human brain using microdialysis.
Acta-Neurochir-Wien 1990;102(3-4):91-7.

Trbojevic Cepe M, Kracun I
Institute of Clinical Laboratory Diagnostics, Zagreb University School of Medicine, Yugoslavia.
Determination of gangliosides in human cerebrospinal fluid by high-performance thin-layer chromatography and direct densitometry.
J-Clin-Chem-Clin-Biochem 1990 Nov;28(11):863-72.